Articles with "lupus" as a keyword



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Systemic Lupus Erythematosus

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Published in 2021 at "Clinical Rheumatology"

DOI: 10.1007/978-981-33-4885-1_14

Abstract: 1.1 What is it? Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various organs of the body, especially the skin, joints, blood, kidneys and central nervous system. "Chronic" means that it… read more here.

Keywords: lupus erythematosus; erythematosus; lupus; rheumatology ... See more keywords
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[Innovations in the pharmaceutical treatment of systemic lupus erythematosus].

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Published in 2022 at "Der Internist"

DOI: 10.1007/s00108-021-01250-3

Abstract: BACKGROUND Systemic lupus erythematosus (SLE) is a heterogeneous disease with a complex pathogenesis. Until now, the choice of therapeutic agents has been limited. OBJECTIVE This review revisits known forms of treatment for SLE and introduces new… read more here.

Keywords: systemic lupus; treatment; innovations pharmaceutical; lupus erythematosus ... See more keywords
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Urinary clusterin—a novel urinary biomarker associated with pediatric lupus renal histopathologic features and renal survival

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Published in 2018 at "Pediatric Nephrology"

DOI: 10.1007/s00467-018-3924-4

Abstract: BackgroundLupus nephritis (LN) is a major risk factor for systemic lupus erythematous (SLE)-related morbidity and mortality. With the aim of bypassing renal biopsy, we analyzed urinary biomarkers for their ability to predict renal histopathologic features… read more here.

Keywords: renal histopathologic; clusterin; urinary clusterin; lupus ... See more keywords
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The behavior of neutrophil extracellular traps and NADPH oxidative activity in pediatric systemic lupus erythematosus: relation to disease activity and lupus nephritis

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Published in 2019 at "Clinical Rheumatology"

DOI: 10.1007/s10067-019-04547-9

Abstract: ObjectivesTo evaluate the neutrophil extracellular traps (NETs) assay and NADPH oxidase (Nox2) activity in pediatric systemic lupus erythematosus (pSLE) in relation to each other and SLE characteristics.MethodsThis cross-sectional study included 50 children and adolescents with… read more here.

Keywords: neutrophil extracellular; correlation; lupus; extracellular traps ... See more keywords
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Splenic calcifications: an unusual finding in systemic lupus erythematosus

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Published in 2022 at "Clinical Rheumatology"

DOI: 10.1007/s10067-022-06161-8

Abstract: A 49-year-old female patient presented to a nearby hospital after experiencing a high-grade fever and myalgias for 6 days. She has an 18-year history of systemic lupus erythematosus (SLE) with joint and renal involvement, treated… read more here.

Keywords: lupus erythematosus; calcifications unusual; lupus; splenic calcifications ... See more keywords
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UCH-L1 Expressed by Podocytes: a Potentially Therapeutic Target for Lupus Nephritis?

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Published in 2017 at "Inflammation"

DOI: 10.1007/s10753-017-0512-x

Abstract: Systemic lupus erythematosus (SLE) is a multisystem disease affecting many organs, and the most severe complication is lupus nephritis. Podocyte injury and loss play vital roles in the pathogenesis of lupus nephritis. Studies have shown… read more here.

Keywords: expressed podocytes; lupus nephritis; uch expressed; lupus ... See more keywords
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Genetic variants of microRNA-146a gene: an indicator of systemic lupus erythematosus susceptibility, lupus nephritis, and disease activity.

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Published in 2020 at "Molecular biology reports"

DOI: 10.1007/s11033-020-05802-y

Abstract: Genetic variations of microRNA encoding genes influence various sorts of diseases by modifying the expression or activity of microRNAs. MicroRNA 146a is an epigenetic regulator of immune response through controlling the type I interferon (IFN)… read more here.

Keywords: lupus; disease activity; microrna 146a; lupus nephritis ... See more keywords
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Retrospective review of the clinical and laboratory data in silent lupus nephritis

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Published in 2021 at "International Urology and Nephrology"

DOI: 10.1007/s11255-021-03066-4

Abstract: To determine the ratio of renal disease necessitating immunosuppressive treatment in lupus patients who are clinically asymptomatic by means of renal disease. It was also examined whether silent lupus nephritis is associated with any of… read more here.

Keywords: renal disease; clinical laboratory; lupus nephritis; disease ... See more keywords
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HPV and systemic lupus erythematosus: a mosaic of potential crossreactions

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Published in 2017 at "Immunologic Research"

DOI: 10.1007/s12026-016-8890-y

Abstract: Etiology, pathogenesis, and immunology of systemic lupus erythematosus (SLE) form a complex, still undeciphered picture that recently has been further made complicated by a new factor of morbidity: human papillomaviruses (HPVs). Indeed, a prevalence of… read more here.

Keywords: systemic lupus; hpv systemic; lupus erythematosus; erythematosus mosaic ... See more keywords
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Systemic Lupus Erythematosus: Considerations in Diagnosis and Management for the Inpatient Dermatologist

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Published in 2020 at "Current Dermatology Reports"

DOI: 10.1007/s13671-020-00312-3

Abstract: Hospitalization of systemic lupus erythematosus (SLE) patients is frequent and most often due to disease flares and infection. Herein, we describe the clinical features and therapy for specific and nonspecific cutaneous manifestations of hospitalized lupus… read more here.

Keywords: systemic lupus; lupus; lupus erythematosus; inpatient dermatologist ... See more keywords
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Hair and Scalp Changes in Cutaneous and Systemic Lupus Erythematosus

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Published in 2018 at "American Journal of Clinical Dermatology"

DOI: 10.1007/s40257-018-0363-8

Abstract: Cutaneous and systemic lupus erythematosus (SLE) commonly involves the hair and scalp. Alopecia can result from direct activity of disease on the scalp or from the state of physical stress in the form of telogen… read more here.

Keywords: hair scalp; systemic lupus; lupus erythematosus; cutaneous systemic ... See more keywords