Neutrophil Heterogeneity Identifies an Association of LAMP1 With Proliferative Lupus Nephritis
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DOI: 10.1002/eji.70022
Abstract: Lupus nephritis (LN) is a severe manifestation of systemic lupus erythematosus (SLE) with limited biomarkers for early detection. While neutrophils contribute to SLE pathogenesis, their phenotypic heterogeneity in disease remains poorly characterized. Here, we used… read more here.
Keywords: lupus; neutrophil heterogeneity; lupus nephritis; lamp1 ... See more keywords
Systemic Lupus Erythematosus
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DOI: 10.1007/978-981-33-4885-1_14
Abstract: 1.1 What is it? Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect various organs of the body, especially the skin, joints, blood, kidneys and central nervous system. "Chronic" means that it… read more here.
Keywords: lupus erythematosus; erythematosus; lupus; rheumatology ... See more keywords
[Innovations in the pharmaceutical treatment of systemic lupus erythematosus].
Sign Up to like & getrecommendations! Published in 2022 at "Der Internist"
DOI: 10.1007/s00108-021-01250-3
Abstract: BACKGROUND Systemic lupus erythematosus (SLE) is a heterogeneous disease with a complex pathogenesis. Until now, the choice of therapeutic agents has been limited. OBJECTIVE This review revisits known forms of treatment for SLE and introduces new… read more here.
Keywords: systemic lupus; treatment; innovations pharmaceutical; lupus erythematosus ... See more keywords
Heterogeneous myocardial contraction detected by speckle tracking echocardiography in systemic lupus erythematosus is associated with complement protein C4: a cross-sectional study from a Swedish tertiary referral centre
Sign Up to like & getrecommendations! Published in 2025 at "Rheumatology International"
DOI: 10.1007/s00296-025-05939-8
Abstract: Although systemic lupus erythematosus (SLE) is associated with an increased risk of cardiovascular disease, conventional echocardiographic measures often fail to detect early myocardial dysfunction. This study assesses left ventricular mechanical dispersion (LVMD) and its associations… read more here.
Keywords: lupus; speckle tracking; pathology; tracking echocardiography ... See more keywords
Urinary clusterin—a novel urinary biomarker associated with pediatric lupus renal histopathologic features and renal survival
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DOI: 10.1007/s00467-018-3924-4
Abstract: BackgroundLupus nephritis (LN) is a major risk factor for systemic lupus erythematous (SLE)-related morbidity and mortality. With the aim of bypassing renal biopsy, we analyzed urinary biomarkers for their ability to predict renal histopathologic features… read more here.
Keywords: renal histopathologic; clusterin; urinary clusterin; lupus ... See more keywords
The behavior of neutrophil extracellular traps and NADPH oxidative activity in pediatric systemic lupus erythematosus: relation to disease activity and lupus nephritis
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Rheumatology"
DOI: 10.1007/s10067-019-04547-9
Abstract: ObjectivesTo evaluate the neutrophil extracellular traps (NETs) assay and NADPH oxidase (Nox2) activity in pediatric systemic lupus erythematosus (pSLE) in relation to each other and SLE characteristics.MethodsThis cross-sectional study included 50 children and adolescents with… read more here.
Keywords: neutrophil extracellular; correlation; lupus; extracellular traps ... See more keywords
Splenic calcifications: an unusual finding in systemic lupus erythematosus
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DOI: 10.1007/s10067-022-06161-8
Abstract: A 49-year-old female patient presented to a nearby hospital after experiencing a high-grade fever and myalgias for 6 days. She has an 18-year history of systemic lupus erythematosus (SLE) with joint and renal involvement, treated… read more here.
Keywords: lupus erythematosus; calcifications unusual; lupus; splenic calcifications ... See more keywords
First case of lupus induced by the Shingrix vaccine: a case report and literature review
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DOI: 10.1007/s10067-025-07529-2
Abstract: The recombinant zoster vaccine (Shingrix) was recently approved for the prevention of herpes zoster reactivation in adults aged ≥ 50 years. While its effectiveness has been widely demonstrated, its safety profile and potential adverse effects remain uncertain.… read more here.
Keywords: lupus; induced lupus; lupus induced; drug ... See more keywords
UCH-L1 Expressed by Podocytes: a Potentially Therapeutic Target for Lupus Nephritis?
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DOI: 10.1007/s10753-017-0512-x
Abstract: Systemic lupus erythematosus (SLE) is a multisystem disease affecting many organs, and the most severe complication is lupus nephritis. Podocyte injury and loss play vital roles in the pathogenesis of lupus nephritis. Studies have shown… read more here.
Keywords: expressed podocytes; lupus nephritis; uch expressed; lupus ... See more keywords
Genetic variants of microRNA-146a gene: an indicator of systemic lupus erythematosus susceptibility, lupus nephritis, and disease activity.
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DOI: 10.1007/s11033-020-05802-y
Abstract: Genetic variations of microRNA encoding genes influence various sorts of diseases by modifying the expression or activity of microRNAs. MicroRNA 146a is an epigenetic regulator of immune response through controlling the type I interferon (IFN)… read more here.
Keywords: lupus; disease activity; microrna 146a; lupus nephritis ... See more keywords
Retrospective review of the clinical and laboratory data in silent lupus nephritis
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DOI: 10.1007/s11255-021-03066-4
Abstract: To determine the ratio of renal disease necessitating immunosuppressive treatment in lupus patients who are clinically asymptomatic by means of renal disease. It was also examined whether silent lupus nephritis is associated with any of… read more here.
Keywords: renal disease; clinical laboratory; lupus nephritis; disease ... See more keywords