Articles with "lupus disease" as a keyword



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Use of the Cutaneous Lupus Disease Area and Severity Index as an outcome measure in clinical trials: a descriptive study

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Published in 2020 at "Clinical and Experimental Dermatology"

DOI: 10.1111/ced.14420

Abstract: This study summarizes the use, since its inception, of the Cutaneous Lupus Disease Area and Severity Index (CLASI) as an outcome measure in clinical studies. We systematically searched the MEDLINE, PubMed, EMBASE and Cochrane databases… read more here.

Keywords: severity index; area severity; disease area; lupus disease ... See more keywords

Longitudinal analysis of varicella-zoster virus-specific antibodies in systemic lupus erythematosus: No association with subclinical viral reactivations or lupus disease activity

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Published in 2018 at "Lupus"

DOI: 10.1177/0961203318770535

Abstract: Systemic lupus erythematosus (SLE) patients are at high risk of herpes zoster. Previously, we found increased immunoglobulin (Ig)G levels against varicella-zoster virus (VZV) in SLE patients compared to controls, while antibody levels against diphtheria and… read more here.

Keywords: vzv igg; disease activity; lupus disease; vzv ... See more keywords

Helios Expression Is Downregulated on CD8+ Treg in Two Mouse Models of Lupus During Disease Progression

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.922958

Abstract: T-cell–mediated autoimmunity reflects an imbalance in this compartment that is not restored by tolerogenic immune cells, e.g., regulatory T cells or tolerogenic dendritic cells (tolDCs). Although studies into T-cell equilibrium have mainly focused on regulatory… read more here.

Keywords: cd8 tregs; expression downregulated; mouse; downregulated cd8 ... See more keywords

Molecular docking of gingerol and shogaol for immunomodulatory effect in lupus disease

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Published in 2024 at "Pharmacy Education"

DOI: 10.46542/pe.2024.243.141146

Abstract: Background: One of the autoimmune diseases associated with high mortality is lupus or Systemic Lupus Erythematosus (SLE). In addition to symptomatic therapy, the treatment management of this condition includes immunomodulatory therapy. Various studies have been… read more here.

Keywords: lupus; gingerol shogaol; lupus disease; gingerol ... See more keywords

Calcineurin inhibitors experience in unplanned pregnancies with active lupus disease: A retrospective observational study.

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Published in 2024 at "International journal of clinical pharmacology and therapeutics"

DOI: 10.5414/cp204528

Abstract: OBJECTIVES To evaluate the use of calcineurin inhibitors (CNIs), specifically tacrolimus, in unplanned pregnancies with active lupus disease among patients with systemic lupus erythematosus (SLE). MATERIALS AND METHODS The study includes data from pregnancies in… read more here.

Keywords: history; active lupus; lupus disease; pregnancies active ... See more keywords