Assessment of Response to B-Cell Depletion Using Rituximab in Cutaneous Lupus Erythematosus
Sign Up to like & getrecommendations! Published in 2018 at "JAMA Dermatology"
DOI: 10.1001/jamadermatol.2018.3793
Abstract: Importance Cutaneous lupus erythematosus (CLE) can be severe and treatment resistant. B-cell depletion therapy (BCDT) with rituximab is well recognized in organ involvement in systemic lupus erythematosus (SLE), but its efficacy in cutaneous manifestations is… read more here.
Keywords: cell depletion; response; lupus erythematosus; bilag grade ... See more keywords
Creation and Validation of Classification Criteria for Discoid Lupus Erythematosus.
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DOI: 10.1001/jamadermatol.2020.1698
Abstract: Importance Classification criteria are the standardized definitions that are used to enroll uniform cohorts for research studies. They emphasize high specificity and are distinct from diagnostic criteria. No universally recognized classification criteria currently exist for… read more here.
Keywords: classification; discoid lupus; dermatology; classification criteria ... See more keywords
Clinical Characteristics of Lupus Erythematosus Panniculitis/Profundus: A Retrospective Review of 61 Patients.
Sign Up to like & getrecommendations! Published in 2020 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2020.2797
Abstract: This case series characterizes the initial presentation and treatment of lupus erythematosus panniculitis/profundus and its association with systemic lupus erythematosus and discoid lupus erythematosus. read more here.
Keywords: panniculitis profundus; lupus erythematosus; erythematosus panniculitis; erythematosus ... See more keywords
Interventions for Cutaneous Disease in Systemic Lupus Erythematosus: Summary of a Cochrane Review.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2021.5485
Abstract: Clinical Question What is the efficacy of interventions for cutaneous disease in systemic lupus erythematosus (SLE) in randomized clinical trials (RCTs)? Bottom Line Available RCT evidence on the management of cutaneous disease in SLE is… read more here.
Keywords: disease; cutaneous disease; systemic lupus; interventions cutaneous ... See more keywords
Treatment With Anifrolumab for Discoid Lupus Erythematosus.
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DOI: 10.1001/jamadermatol.2022.5242
Abstract: This case report describes 2 women with severe and refractory discoid lupus erythematosus that was treated with anifrolumab. read more here.
Keywords: lupus erythematosus; treatment anifrolumab; discoid lupus;
Vascular-Targeted Therapy for Systemic Lupus Erythematosus-Associated Vasculitis.
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DOI: 10.1001/jamadermatol.2023.0077
Abstract: This case report describes a woman in her 40s with a medical history of systemic lupus erythematosus with 1 year of tender papules, plaques, and progressive ulcers on her hands and feet. read more here.
Keywords: lupus erythematosus; targeted therapy; systemic lupus; vascular targeted ... See more keywords
Assessment of Clinical Response to Anifrolumab in Patients With Refractory Discoid Lupus Erythematosus.
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DOI: 10.1001/jamadermatol.2023.0175
Abstract: This case series examines the efficacy of anifrolumab as a therapeutic option for patients with lupus erythematosus. read more here.
Keywords: clinical response; patients refractory; anifrolumab patients; response anifrolumab ... See more keywords
Lupus erythematosus eosinophil cells in a pleural effusion
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DOI: 10.1002/dc.24692
Abstract: Lupus erythematosus (LE) cell is most commonly a macrophage or neutrophil that contains in its cytoplasm a hematoxylin or LE body. Such body is formed by altered nuclear material derived from the patient leukocytes. Hematoxylin… read more here.
Keywords: cells pleural; eosinophil cells; lupus erythematosus; pleural effusion ... See more keywords
Dnase1‐deficient mice spontaneously develop a systemic lupus erythematosus‐like disease
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DOI: 10.1002/eji.201847875
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease that has high morbidity and can result in multi‐organ damage. SLE is characterized by dysregulated activation of T‐ and B‐lymphocytes and the production of autoantibodies directed against… read more here.
Keywords: dnase1 deficient; systemic lupus; lupus erythematosus; disease ... See more keywords
Systemic lupus erythematosus patients contain B‐cell receptor repertoires sensitive to immunosuppressive drugs
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DOI: 10.1002/eji.202149596
Abstract: Immune repertoire (IR) during treatment may be a surrogate biomarker for disease response. Changes of the IR in systemic lupus erythematosus patients in response to immunosuppressive drugs were identified in ten SLE patients. Patients provided… read more here.
Keywords: sensitive group; erythematosus patients; immunosuppressive drugs; group ... See more keywords
Persistently active interferon-γ pathway and expansion of T-bet+ B cells in a subset of patients with childhood-onset systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250319
Abstract: Systemic lupus erythematosus (SLE) is an autoimmune disease causing significant morbidity and mortality, despite important improvements in its management in the last decades. The objective of this work is to investigate the role of IFN-γ… read more here.
Keywords: lupus erythematosus; ifn; systemic lupus; bet ... See more keywords