Autoantibody Profiling in Lupus Patients using Synthetic Nucleic Acids
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23910-5
Abstract: Autoantibodies to nuclear components of cells (antinuclear antibodies, ANA), including DNA (a-DNA), are widely used in the diagnosis and subtyping of certain autoimmune diseases, including systemic lupus erythematosus (SLE). Despite clinical use over decades, precise,… read more here.
Keywords: profiling lupus; dna; lupus patients; synthetic nucleic ... See more keywords
Relationships between type 1 IFN signatures and clinical features of the newly-onset lupus patients in Japan.
Sign Up to like & getrecommendations! Published in 2023 at "Modern rheumatology"
DOI: 10.1093/mr/road015
Abstract: OBJECTIVES To investigate the relationships between type 1 interferon (T1-IFN) signatures and clinical characteristic in lupus patients. METHODS We examined 49 patients with newly-onset patients, who were diagnosed between 1999 and 2017. The patients treated… read more here.
Keywords: lupus patients; relationships type; type ifn; ifn signatures ... See more keywords
AB0493 Blys upregulation is related to lymphopenia in systemic erythematous lupus patients
Sign Up to like & getrecommendations! Published in 2017 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2017-eular.4186
Abstract: Background B lymphocyte stimulator factor (BLyS) is produced by wide range of cells of the immune system, and has proven to be a key factor in the selection and survival of B cells. BLyS is… read more here.
Keywords: blys; blys upregulation; blys levels; lupus patients ... See more keywords
FRI0255 LOW ATTENUATION NON-CALCIFIED CORONARY PLAQUES AND POSITIVE REMODELING INDEX: MARKERS OF VULNERABLE CORONARY PLAQUES IN SYSTEMIC LUPUS ERYTHEMATOSUS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.5908
Abstract: Background: The presence of low attenuation noncalcified plaque (LANCP) and positive remodeling index (RI) are characteristic vessel changes in unstable coronary plaques. LANCP ( read more here.
Keywords: positive remodeling; remodeling index; lupus patients; coronary plaques ... See more keywords
OP0073 SINGLE-CELL TRANSCRIPTOMICS UNCOVERS DEFECTIVE BONE MARROW EARLY B CELL DEVELOPMENT IN A SUBSET OF LUPUS PATIENTS ASSOCIATED WITH AGGRAVATED INFLAMMATION
Sign Up to like & getrecommendations! Published in 2021 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2021-eular.3061
Abstract: Systemic lupus erythematosus (SLE) is a systemic autoimmune disease that occurs when the body’s immune system attacks own tissues and organs. B cells play a central role in SLE pathogenesis by producing autoantibodies as well… read more here.
Keywords: bone marrow; cell; lupus patients; lupus ... See more keywords
AB0562 LIVER ENZYME ABNORMALITIES IN HOSPITALIZED LUPUS PATIENTS – A RETROSPECTIVE STUDY
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2022-eular.4889
Abstract: Around 25% to 50% of lupus patients may present with alterations in the liver enzymes of variable severity including fulminant hepatic failure.1To study the prevalence, aetiology and the outcome in lupus patients hospitalized with liver… read more here.
Keywords: rheumatology; liver enzyme; enzyme abnormalities; liver enzymes ... See more keywords
Intestinal Dysbiosis Is Associated with Altered Short-Chain Fatty Acids and Serum-Free Fatty Acids in Systemic Lupus Erythematosus
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2017.00023
Abstract: Metabolic impairments are a frequent hallmark of systemic lupus erythematosus (SLE). Increased serum levels of free fatty acids (FFA) are commonly found in these patients, although the underlying causes remain elusive. Recently, it has been… read more here.
Keywords: intestinal dysbiosis; fatty acids; lupus patients; ffa ... See more keywords