Articles with "lurasidone" as a keyword



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Lurasidone‐induced hyperosmolar hyperglycemic syndrome: A case report

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Published in 2022 at "Neuropsychopharmacology Reports"

DOI: 10.1002/npr2.12259

Abstract: Lurasidone has few metabolic adverse effects and is recommended as an alternative when other antipsychotic drugs considerably increase body weight or blood sugar concentrations. read more here.

Keywords: hyperosmolar hyperglycemic; lurasidone induced; induced hyperosmolar; lurasidone ... See more keywords
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Altered responsiveness of the antioxidant system in chronically stressed animals: modulation by chronic lurasidone treatment.

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Published in 2022 at "Psychopharmacology"

DOI: 10.1007/s00213-022-06140-6

Abstract: RATIONALE Although the occurrence of stressful events is very common during life, their impact may be different depending on the experience severity and duration. Specifically, acute challenges may trigger adaptive responses and even improve the… read more here.

Keywords: lurasidone; treatment; modulation; stress ... See more keywords
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Practical Guidance on the Use of Lurasidone for the Treatment of Adults with Schizophrenia

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Published in 2019 at "Neurology and Therapy"

DOI: 10.1007/s40120-019-0138-z

Abstract: IntroductionLurasidone is an atypical antipsychotic that was approved in Europe in 2014 for the treatment of schizophrenia in adults aged ≥ 18 years. Clinical experience with lurasidone in Europe is currently limited, and there is therefore a… read more here.

Keywords: treatment adults; lurasidone treatment; adults schizophrenia; practical guidance ... See more keywords
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Long-Term Assessment of Lurasidone in Schizophrenia: Post Hoc Analysis of a 12-Month, Double Blind, Active-Controlled Trial and 6-Month Open-Label Extension Study

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Published in 2020 at "Neurology and Therapy"

DOI: 10.1007/s40120-020-00221-4

Abstract: A post hoc analysis of a double-blind (DB) active control trial and an open-label extension (OLE) study was conducted to evaluate the long-term effects of lurasidone in patients with schizophrenia. In the DB trial, patients… read more here.

Keywords: trial; long term; risperidone; lurasidone ... See more keywords
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Lurasidone-β-cyclodextrin complexes: Physicochemical characterization and comparison of their antidepressant, antipsychotic activities against that of self microemulsifying formulation

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Published in 2018 at "Journal of Molecular Structure"

DOI: 10.1016/j.molstruc.2017.12.042

Abstract: Abstract Lurasidone hydrochloride (LHD) is an atypical antipsychotic drug has poor aqueous solubility and low bioavailability (9–19%). This study describes effect of different methods of complex formation with β-cyclodextrin (BCD) on enhancement of dissolution and… read more here.

Keywords: bcd; self microemulsifying; cyclodextrin; antidepressant antipsychotic ... See more keywords
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Lurasidone in post-menopausal females with major depressive disorder with mixed features: Post-hoc analysis of a placebo-controlled trial

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Published in 2017 at "Progress in Neuro-Psychopharmacology and Biological Psychiatry"

DOI: 10.1016/j.pnpbp.2017.05.002

Abstract: Background: Several studies have found that depressed, post‐menopausal females may respond differently to antidepressants compared to pre‐menopausal females. The atypical antipsychotic lurasidone, whose mechanism of action differs from SSRIs and other standard antidepressants, was shown… read more here.

Keywords: menopausal; post menopausal; placebo; analysis ... See more keywords
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TULIP study: Trail of Lurasidone in bipolar disorder in Pakistan☆

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Published in 2021 at "Saudi Journal of Biological Sciences"

DOI: 10.1016/j.sjbs.2020.11.044

Abstract: Background This study examined usefulness and efficiency of Lurasidone in appraisal with the placebo as for the treatment of Bipolar Disorders. Methods Seven treatment centers in Pakistan were selected for the purpose of starting a… read more here.

Keywords: tulip study; drug; study trail; lurasidone ... See more keywords
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Long-Term Effectiveness of Lurasidone in Pediatric Bipolar Depression: Response, Remission and Recovery.

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Published in 2021 at "CNS spectrums"

DOI: 10.1017/s1092852920002345

Abstract: BACKGROUND Bipolar disorder frequently has an early onset, with an estimated 1.8% prevalence of bipolar I disorder in children and adolescents. Childhood onset of bipolar disorder is typically associated with a chronic, severe, and disabling… read more here.

Keywords: score; lurasidone; response remission; bipolar depression ... See more keywords
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Lurasidone and risk of metabolic syndrome: results from short and long-term studies in patients with bipolar depression.

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Published in 2023 at "CNS spectrums"

DOI: 10.1017/s1092852923001190

Abstract: OBJECTIVE The elevated prevalence of metabolic syndrome (MetS) in patients with depression has been associated with increased mortality. This post hoc analysis assessed the effect of treatment with lurasidone on risk of MetS in patients… read more here.

Keywords: bipolar depression; depression; adjunctive therapy; patients bipolar ... See more keywords
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Efficacy and Safety of Lurasidone in a Younger Population With Bipolar Depression: Pooled Post-hoc Analysis of Two Placebo-controlled Studies

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Published in 2023 at "CNS Spectrums"

DOI: 10.1017/s1092852923001864

Abstract: Abstract Introduction Early onset of bipolar disorder is associated with high rates of psychiatric comorbidity (e.g., anxiety disorders, ADHD, PTSD), high rates of recurrence, and marked impairment in functioning and quality of life. The aim… read more here.

Keywords: bipolar depression; depression; placebo; analysis ... See more keywords
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A network meta-analysis of the dose-response effects of lurasidone on acute schizophrenia.

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Published in 2021 at "Scientific reports"

DOI: 10.1038/s41598-021-84836-z

Abstract: We compared the efficacy, safety, and acceptability of lurasidone at different doses to establish the dose-response relationships of lurasidone therapeutic and adverse effects in acute schizophrenia. Included trials were 4- to 16-week, fixed-dose, randomized controlled… read more here.

Keywords: dose response; acute schizophrenia; lurasidone; day ... See more keywords