Silencing GOLGA8B inhibits cell invasion and metastasis by suppressing STAT3 signaling pathway in lung squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical science"
DOI: 10.1042/cs20220128
Abstract: Changes to some Golgi subfamily member proteins are reported to be involved in tumor metastasis. However, the functional role and potential mechanism of the Golgi A8 family member B (GOLGA8B) in lung squamous cell carcinoma… read more here.
Keywords: metastasis; cell; golga8b; invasion ... See more keywords
Transcription factor NFIC functions as a tumor suppressor in lung squamous cell carcinoma progression by modulating lncRNA CASC2
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DOI: 10.1080/15384101.2021.1995130
Abstract: ABSTRACT Nuclear factor I (NFI) family is emerging found playing oncogenic or tumor-suppressive potential in cancers. However, the function and underlying mechanisms of NFIC, in the progression of Lung Squamous Cell Carcinoma (LUSC) remain unclear.… read more here.
Keywords: cell; squamous cell; casc2; lusc ... See more keywords
MIR205HG facilitates carcinogenesis of lung squamous cell carcinoma in vitro revealed by long noncoding RNA profiling.
Sign Up to like & getrecommendations! Published in 2020 at "Acta biochimica et biophysica Sinica"
DOI: 10.1093/abbs/gmaa006
Abstract: As a subtype of non-small-cell lung cancer, lung squamous cell carcinoma (LUSC) accounts for one-fifth of all lung cancers. Unfortunately, no specific targetable aberration has yet been identified. Hence, it is of huge urgency and… read more here.
Keywords: cell carcinoma; squamous cell; lusc; cell ... See more keywords
Connexin43 Promotes the Invasion and Metastasis of Lung Squamous Cell Carcinoma via GJIC‐Dependent Ca2+/ERK Signaling Activation
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DOI: 10.1111/cas.70076
Abstract: Lung squamous cell carcinoma (LUSC) is an extremely metastatic cancer with limited available treatment and poor outcomes. Connexin43 (Cx43) is frequently overactivated and positively correlated with tumorigenesis in many cancers, including breast cancer and lung… read more here.
Keywords: lung; lusc; cell; ca2 ... See more keywords
PSMA1, a Poor Prognostic Factor, Promotes Tumor Growth in Lung Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Disease Markers"
DOI: 10.1155/2023/5386635
Abstract: Lung squamous cell carcinoma (LUSC) has a poor clinical prognosis and lacks effective targeted therapy. This study is aimed at investigating the role of PSMA1 (proteasome subunit alpha type-1) in LUSC. The differential expression genes… read more here.
Keywords: cell carcinoma; cell; squamous cell; lusc ... See more keywords
Identification of Clinical Prognostic Regulators and Analysis of Ferroptosis-Related Signatures in the Tumor Immune Microenvironment in Lung Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2023 at "Disease Markers"
DOI: 10.1155/2023/9155944
Abstract: Objective Lung squamous cell carcinoma (LUSC) is a common respiratory malignancy and presents an increasing prevalence. Ferroptosis is a newly identified controlled cell death that has captured clinical attention worldwide. However, the ferroptosis-related lncRNA expression… read more here.
Keywords: cell; microenvironment; ferroptosis related; risk ... See more keywords
Assessment of MXD3 Expression as a Predictor of Survival in Lung Squamous Cell Carcinoma
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Genomics"
DOI: 10.1155/ijog/7355595
Abstract: Backgrounds and Aims: Lung squamous cell carcinoma (LUSC) represents a significant challenge in oncology, necessitating the identification of novel prognostic markers and therapeutic targets. This study is aimed at investigating the oncogenic role of MXD3… read more here.
Keywords: mxd3 expression; lusc; squamous cell; expression ... See more keywords
Abstract 6656: Expression pattern and clinicopathological implication of B7 family immune checkpoints, VTCN1 and HHLA2, in non-small cell lung cancer
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DOI: 10.1158/1538-7445.am2023-6656
Abstract: Background: Efforts are needed to discover novel immunotherapeutic targets in non-responders of current immunotherapies. VTCN1 (B7-H4/B7x/B7S1) and HHLA2 (B7-H7/B7y) are B7 family co-inhibitory molecules reported to be expressed in PD-L1-negative or EGFR-mutant lung adenocarcinoma (LUAD).… read more here.
Keywords: cell; expression; vtcn1 hhla2; lusc ... See more keywords
Abstract 3040: Memantine, (a dual α7-nAChR/NMDAR antagonist) displays anti-tumor activity in human squamous cell lung cancer
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-3040
Abstract: of the study: Squamous cell lung carcinoma (LUSC), also called epidermoid carcinoma, is a type of non-small cell lung cancer (NSCLC) that typically develops in one of the air passages, or bronchi, of the lungs.… read more here.
Keywords: cancer; lung; lusc; cell ... See more keywords
Abstract 7232: KDM1A/UTX Mutations Modulate Innate Immune Responses to Influence Immunotherapy Outcomes in Lung Squamous Cell Carcinoma
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DOI: 10.1158/1538-7445.am2025-7232
Abstract: Immunotherapy has come of age for lung cancers, especially lung squamous cell carcinoma (LUSC), which lacks targeted therapies . KDM6A/UTX is frequently mutated in LUSC and is associated with poor prognosis. However, the mechanisms by… read more here.
Keywords: kdm6a utx; utx mutations; immunotherapy; lusc ... See more keywords
Integration of QTL and comprehensive analysis in the circulating inflammatory cytokines for pan-cancer
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DOI: 10.1186/s12885-024-12726-4
Abstract: Chemokines and cytokines are components of the tumor microenvironment and also influence tumorigenesis and its composition. However, whether they genetically proxy tumorigenesis is unclear. For causal inferences, eQTL and pQTL were used to determine the… read more here.
Keywords: cancer; analysis; lusc; microenvironment ... See more keywords