LuxS/AI-2 system is involved in fluoroquinolones susceptibility in Streptococcus suis through overexpression of efflux pump SatAB.
Sign Up to like & getrecommendations! Published in 2019 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2019.05.006
Abstract: Increasing resistance to fluoroquinolones (FQs), such as norfloxacin and enrofloxacin, supports the need for the discovery of novel molecules and alternative approaches in antimicrobial therapy. Quorum sensing (QS) is a promising target for next-generation anti-infective… read more here.
Keywords: system; luxs; streptococcus suis; susceptibility streptococcus ... See more keywords
Clostridioides difficile LuxS mediates inter-bacterial interactions within biofilms
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46143-6
Abstract: The anaerobic gut pathogen, Clostridioides difficile, forms adherent biofilms that may play an important role in recurrent C. difficile infections. The mechanisms underlying C. difficile community formation and inter-bacterial interactions are nevertheless poorly understood. C.… read more here.
Keywords: within biofilms; clostridioides difficile; bacterial interactions; inter bacterial ... See more keywords
Investigation of LuxS-mediated quorum sensing in Klebsiella pneumoniae
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical Microbiology"
DOI: 10.1099/jmm.0.001148
Abstract: Introduction Autoinducer-2 (AI-2) quorum sensing is a bacterial communication system that responds to cell density. The system requires luxS activity to produce AI-2, which can regulate gene expression and processes such as biofilm formation. Aim… read more here.
Keywords: biofilm formation; formation; quorum sensing; expression ... See more keywords
Role of metAB in Methionine Metabolism and Optimal Chicken Colonization in Campylobacter jejuni
Sign Up to like & getrecommendations! Published in 2020 at "Infection and Immunity"
DOI: 10.1128/iai.00542-20
Abstract: Campylobacter jejuni is a zoonotic pathogen and is one of the leading causes of human gastroenteritis worldwide. C. jejuni IA3902 (representative of the sheep abortion clone) is genetically similar to C. jejuni W7 (representative of… read more here.
Keywords: metab; luxs; chicken colonization; ia3902 luxs ... See more keywords
AI-2/LuxS Quorum Sensing System Promotes Biofilm Formation of Lactobacillus rhamnosus GG and Enhances the Resistance to Enterotoxigenic Escherichia coli in Germ-Free Zebrafish
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.00610-22
Abstract: Lactobacillus rhamnosus GG is a widely used probiotic to improve host intestinal health, promote growth, reduce diarrhea, and modulate immunity. In recent years, the bacterial quorum sensing system has attracted much attention; however, there has… read more here.
Keywords: system; free zebrafish; luxs; sensing system ... See more keywords
The Role of luxS in Campylobacter jejuni Beyond Intercellular Signaling
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02572-22
Abstract: Campylobacter jejuni is the world's leading foodborne bacterial pathogen of gastrointestinal disease in humans. C. jejuni is a fastidious but widespread organism and the most frequently reported zoonotic pathogen in the European Union since 2005.… read more here.
Keywords: campylobacter jejuni; luxs mutant; role; luxs ... See more keywords
Virtual Screening and In Vitro Experimental Verification of LuxS Inhibitors for Escherichia coli O157:H7
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03502-22
Abstract: E. coli O157:H7 is a foodborne pathogen of public health importance. Quorum sensing (QS) is a form of bacterial communication that can regulate various group behaviors, including biofilm formation. ABSTRACT Enterohemorrhagic Escherichia coli O157:H7 is… read more here.
Keywords: virtual screening; coli o157; luxs; biofilm formation ... See more keywords
Effects of metformin on Streptococcus suis LuxS/AI-2 quorum sensing system and biofilm formation.
Sign Up to like & getrecommendations! Published in 2023 at "Microbial pathogenesis"
DOI: 10.2139/ssrn.4352887
Abstract: Streptococcus suis (S. suis) regulates biofilm formation through LuxS/AI-2 quorum sensing system, increasing drug resistance and exacerbating infection. The anti-hyperglycaemic agent metformin has anti-bacterial and anti-biofilm activities. This study aimed to investigate the anti-biofilm and… read more here.
Keywords: suis; luxs; biofilm formation; showed metformin ... See more keywords
Baicalein Inhibits the Staphylococcus aureus Biofilm and the LuxS/AI-2 System in vitro
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s406243
Abstract: Introduction Staphylococcus aureus (S. aureus) is a common cause of mastitis in dairy cows, a condition that has a significant economic impact. S. aureus displays quorum sensing (QS) system-controlled virulence characteristics, like biofilm formation, that… read more here.
Keywords: system; luxs; bai; staphylococcus aureus ... See more keywords
The Role of luxS in the Middle Ear Streptococcus pneumoniae Isolate 947
Sign Up to like & getrecommendations! Published in 2022 at "Pathogens"
DOI: 10.3390/pathogens11020216
Abstract: The LuxS protein, encoded by luxS, is required for the production of autoinducer 2 (AI-2) in Streptococcus pneumoniae. The AI-2 molecule serves as a quorum sensing signal, and thus regulates cellular processes such as carbohydrate… read more here.
Keywords: luxs middle; pneumoniae; luxs; role luxs ... See more keywords