Left ventricular ejection fraction decrease related to BRAF and/or MEK inhibitors in metastatic melanoma patients: A retrospective analysis
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.2922
Abstract: BRAF and MEKis have revolutionized the management of BRAFV600‐mutated melanoma patients. Left ventricular ejection fraction decrease (LVEF‐D) related to these treatments has not been thoroughly evaluated to date. The main objective of this study was… read more here.
Keywords: melanoma; lvef; braf mekis; ventricular ejection ... See more keywords
Classifying heart failure based on ejection fraction: imperfect but enduring
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2470
Abstract: For decades, left ventricular ejection fraction (LVEF) has been the mainstay metric for classifying patients within clinical trials for heart failure (HF). Nearly all landmark clinical outcome trials resulting in therapeutic advances for patients with… read more here.
Keywords: ejection fraction; heart failure; lvef;
Combined assessment of left ventricular end-diastolic pressure and ejection fraction by left ventriculography predicts long-term outcomes of patients with ST-segment elevation myocardial infarction
Sign Up to like & getrecommendations! Published in 2017 at "Heart and Vessels"
DOI: 10.1007/s00380-017-1080-6
Abstract: In patients with ST-segment elevation myocardial infarction (STEMI), it is unclear if combined assessment of left ventricular end-diastolic pressure (LVEDP) and left ventricular ejection fraction (LVEF) improves prediction of major adverse cardiac events (MACE). We… read more here.
Keywords: lvef; myocardial infarction; group; patients segment ... See more keywords
Left ventricular contractile performance and heart failure in patients with left ventricular ejection fraction more than 40%
Sign Up to like & getrecommendations! Published in 2020 at "Heart and Vessels"
DOI: 10.1007/s00380-020-01641-w
Abstract: Heart failure (HF) with mid-range left ventricular ejection fraction (LVEF) (HFmrEF) is considered a new category of HF and LVEF read more here.
Keywords: contractile performance; heart; left ventricular; lvef ... See more keywords
Association between left ventricular ejection fraction and mortality after Bentall procedure
Sign Up to like & getrecommendations! Published in 2022 at "Heart and Vessels"
DOI: 10.1007/s00380-022-02028-9
Abstract: Root infection or dissection involving coronary artery frequently necessitates an emergent Bentall procedure, with low left ventricular ejection fraction (LVEF). In contrast, concerning an elective Bentall for aneurysm, surgeons should balance the risk and benefit… read more here.
Keywords: bentall procedure; bentall; lvef; mortality ... See more keywords
High‐sensitivity cardiac troponin T, left ventricular function, and outcome in non–ST elevation acute coronary syndrome
Sign Up to like & getrecommendations! Published in 2018 at "American Heart Journal"
DOI: 10.1016/j.ahj.2017.11.012
Abstract: Background Cardiac troponin (cTn) levels reflect infarct size and depressed left ventricular ejection fraction (LVEF) in patients with non–ST elevation acute coronary syndrome (NSTE‐ACS). However, there is very limited information on whether cTn measured with… read more here.
Keywords: lvef; cardiac troponin; acute coronary; non elevation ... See more keywords
Fluctuation of the left ventricular ejection fraction in patients with HER2-positive early breast cancer treated by 12 months of adjuvant trastuzumab.
Sign Up to like & getrecommendations! Published in 2018 at "Breast"
DOI: 10.1016/j.breast.2018.06.001
Abstract: BACKGROUND Cardiac toxicity with a decrease of the left ventricular ejection fraction (LVEF) is the main side effect induced by trastuzumab. This study reports the fluctuation of LVEF over the 12 months of adjuvant trastuzumab… read more here.
Keywords: ejection fraction; lvef; trastuzumab; ventricular ejection ... See more keywords
HIF-1α Cardioprotection in COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2022 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2021.12.001
Abstract: Myocardial injury with sustained cardiac involvement is noted in more than half (58%) of patients and can be detected months after SARS-CoV-2 infection. SARS-CoV-2 infection directly triggers respiratory illness and frequently leads to both pulmonary… read more here.
Keywords: low lvef; hif; sars cov; covid ... See more keywords
Left Ventricular Ejection Fraction in Patients With Acute Heart Failure: A Limited Tool?
Sign Up to like & getrecommendations! Published in 2017 at "Revista espanola de cardiologia"
DOI: 10.1016/j.rec.2016.11.029
Abstract: It is common to classify patients with either acute or chronic heart failure (HF) based on their left ventricular ejection fraction (LVEF) at presentation—both in clinical practice and in research studies, including practice-defining trials. Although… read more here.
Keywords: ejection fraction; left ventricular; heart failure; lvef ... See more keywords
Retraining an Artificial Intelligence Algorithm to Calculate Left Ventricular Ejection Fraction in Pediatrics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of cardiothoracic and vascular anesthesia"
DOI: 10.1053/j.jvca.2022.05.004
Abstract: OBJECTIVES Identifying patients with low left ventricular ejection fraction (LVEF) and monitoring LVEF responses to treatment are important clinical goals. Can a deep-learning algorithm predict pediatric LVEF within clinically acceptable error? DESIGN The study authors… read more here.
Keywords: ventricular ejection; lvef; artificial intelligence; ejection fraction ... See more keywords
Cardiotoxicity in metastatic melanoma patients treated with BRAF and MEK inhibitors in a real-world setting
Sign Up to like & getrecommendations! Published in 2021 at "Acta Oncologica"
DOI: 10.1080/0284186x.2021.1992010
Abstract: Abstract Background Combination therapy with BRAF and MEK inhibitors (BRAF/MEKi) has significantly improved the outcome for patients with BRAF-mutated melanoma. A reduction in left ventricular ejection fraction (LVEF) is a known side effect during treatment… read more here.
Keywords: mek inhibitors; lvef; braf mek; braf meki ... See more keywords