The crystal structure of Ac-AChBP in complex with α-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
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DOI: 10.1007/s13238-017-0426-2
Abstract: The α3* nAChRs, which are considered to be promising drug targets for problems such as pain, addiction, cardiovascular function, cognitive disorders etc., are found throughout the central and peripheral nervous system. The α-conotoxin (α-CTx) LvIA… read more here.
Keywords: mechanism selectivity; lvia; nachr subtypes; structure ... See more keywords