Discovery, Characterization, and Engineering of LvIC, an α4/4-Conotoxin That Selectively Blocks Rat α6/α3β4 Nicotinic Acetylcholine Receptors.
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DOI: 10.1021/acs.jmedchem.2c01786
Abstract: α6β4 nicotinic acetylcholine receptors (nAChRs) are expressed in the central and peripheral nervous systems, but their functions are not fully understood, largely because of a lack of specific ligands. Here, we characterized a novel α-conotoxin,… read more here.
Keywords: discovery characterization; acetylcholine receptors; nicotinic acetylcholine; lvic ... See more keywords