Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease.
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DOI: 10.1016/j.ejmech.2017.12.080
Abstract: A series of LX2343 derivatives were designed, synthesized and evaluated as neuroprotective agents for Alzheimer's disease (AD) in vitro. Most of the compounds displayed potent neuroprotective activities. Especially for compound A6, exhibited a remarkable EC50 value… read more here.
Keywords: lx2343 derivatives; neuroprotective agents; alzheimer disease; disease ... See more keywords