LxCxD motif of the APC/C coactivator subunit FZR1 is critical for interaction with the retinoblastoma protein.
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DOI: 10.1016/j.yexcr.2021.112632
Abstract: Retinoblastoma protein (pRB) regulates cell cycle by utilizing different regions of its pocket domain for interacting with E2F family of transcription factors and with cellular and viral proteins containing an LxCxE motif. The LxCxE motif… read more here.
Keywords: protein; prb; fzr1; lxcxe motif ... See more keywords