Moxibustion at CV4 alleviates atherosclerotic lesions through activation of the LXRα/ABCA1 pathway in apolipoprotein-E-deficient mice
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DOI: 10.1136/acupmed-2016-011317
Abstract: Objectives: To investigate the anti-atherogenic effect of moxibustion and whether it is mediated through the reverse cholesterol transport process. Methods: 8-week-old male apolipoprotein E deficient (ApoE−/− knockout) mice were randomly divided into two groups (n=10… read more here.
Keywords: moxibustion; thoracic aorta; lxr abca1; atherosclerotic lesions ... See more keywords
5-HT3 Antagonist Ondansetron Increases apoE Secretion by Modulating the LXR-ABCA1 Pathway
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DOI: 10.3390/ijms20061488
Abstract: Apolipoprotein E (apoE) is linked to the risk for Alzheimer’s disease (AD) and thus has been suggested to be an important therapeutic target. In our drug screening effort, we identified Ondansetron (OS), an FDA-approved 5-HT3… read more here.
Keywords: secretion; abca1 pathway; lxr abca1; apoe secretion ... See more keywords