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Varespladib (LY315920) and Methyl Varespladib (LY333013) Abrogate or Delay Lethality Induced by Presynaptically Acting Neurotoxic Snake Venoms

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Published in 2020 at "Toxins"

DOI: 10.3390/toxins12020131

Abstract: The phospholipase A2 (PLA2) inhibitor Varespladib (LY315920) and its orally bioavailable prodrug, methyl-Varespladib (LY333013) inhibit PLA2 activity of a wide variety of snake venoms. In this study, the ability of these two forms of Varespladib… read more here.

Keywords: presynaptically acting; varespladib ly315920; varespladib; snake venoms ... See more keywords