Matrix metalloproteinase-12 produced by Ly6Clow macrophages prolongs the survival after myocardial infarction by preventing neutrophil influx.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.04.007
Abstract: BACKGROUND Various immune cells are involved in different phases of cardiac repair after myocardial infarction (MI). Especially, Ly6Clow M2-like macrophages (Ly6Clo macrophages) are vital for cardiac repair after MI. However, the molecular mechanisms how Ly6Clo… read more here.
Keywords: mmp; infarcted heart; mmp12 mice; ly6clo macrophages ... See more keywords
Occurrences and Functions of Ly6Chi and Ly6Clo Macrophages in Health and Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.901672
Abstract: Macrophages originating from the yolk sac or bone marrow play essential roles in tissue homeostasis and disease. Bone marrow-derived monocytes differentiate into Ly6Chi and Ly6Clo macrophages according to the differential expression of the surface marker… read more here.
Keywords: ly6chi ly6clo; functions ly6chi; ly6clo macrophages; disease ... See more keywords