Articles with "ly6k" as a keyword



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LY6K-AS lncRNA is a lung adenocarcinoma prognostic biomarker and regulator of mitotic progression

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Published in 2021 at "Oncogene"

DOI: 10.1038/s41388-021-01696-7

Abstract: Recent advances in genomics unraveled several actionable mutational drivers in lung cancer, leading to promising therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitors. However, the tumors’ acquired resistance to the newly-developed as well… read more here.

Keywords: lung adenocarcinoma; mitotic progression; lung cancer; ly6k ... See more keywords
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Abstract LB010: LY6K depletion modulates TGF-β and EGF signaling

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-lb010

Abstract: Lymphocyte antigen 6 complex locus K (LY6K), a glycosylphosphatidylinositol-anchored protein, plays a dynamic role in cancer metastasis. In the current study, we deciphered the effects of LY6K on transforming growth factor-β (TGF-β) and epidermal growth… read more here.

Keywords: ly6k; tgf egf; egf signaling; ly6k depletion ... See more keywords