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Published in 2021 at "Oncogene"
DOI: 10.1038/s41388-021-01696-7
Abstract: Recent advances in genomics unraveled several actionable mutational drivers in lung cancer, leading to promising therapies such as tyrosine kinase inhibitors and immune checkpoint inhibitors. However, the tumors’ acquired resistance to the newly-developed as well…
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Keywords:
lung adenocarcinoma;
mitotic progression;
lung cancer;
ly6k ... See more keywords
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Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-lb010
Abstract: Lymphocyte antigen 6 complex locus K (LY6K), a glycosylphosphatidylinositol-anchored protein, plays a dynamic role in cancer metastasis. In the current study, we deciphered the effects of LY6K on transforming growth factor-β (TGF-β) and epidermal growth…
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Keywords:
ly6k;
tgf egf;
egf signaling;
ly6k depletion ... See more keywords