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Inhibitory activities of kukoamines A and B from Lycii Cortex on amyloid aggregation related to Alzheimer’s disease and type 2 diabetes

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Published in 2019 at "Journal of Natural Medicines"

DOI: 10.1007/s11418-019-01337-0

Abstract: Alzheimer’s diseases (AD) and type 2 diabetes (T2D) are two age-related diseases characterized by amyloid fibrillogenesis. Prevention of amyloid aggregation is a promising therapeutic strategy for AD and T2D. Two spermine alkaloids, kukoamines A and B, isolated… read more here.

Keywords: aggregation; activities kukoamines; inhibitory activities; type diabetes ... See more keywords