The TEAD family transcription factor Scalloped regulates blood progenitor maintenance and proliferation in Drosophila through PDGF/VEGFR receptor (Pvr) signaling.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental biology"
DOI: 10.1016/j.ydbio.2017.03.016
Abstract: The Drosophila lymph gland is a well-characterized hematopoietic organ in which a population of multipotent stem-like progenitors is maintained by a combination of signals from different cellular populations within the organ. The lymph gland serves… read more here.
Keywords: progenitor maintenance; proliferation; lymph gland; gland ... See more keywords
Dual control of dopamine in Drosophila myeloid‐like progenitor cell proliferation and regulation of lymph gland growth
Sign Up to like & getrecommendations! Published in 2022 at "EMBO reports"
DOI: 10.15252/embr.202152951
Abstract: In Drosophila, definitive haematopoiesis takes place in a specialized organ termed “lymph gland”. It harbours multi‐potent stem‐like blood progenitor cells whose development controls overall growth of this haematopoietic tissue and formation of mature blood cells.… read more here.
Keywords: lymph gland; cell; growth; progenitor ... See more keywords
Drosophila as a Model to Study Cellular Communication Between the Hematopoietic Niche and Blood Progenitors Under Homeostatic Conditions and in Response to an Immune Stress
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.719349
Abstract: In adult mammals, blood cells are formed from hematopoietic stem progenitor cells, which are controlled by a complex cellular microenvironment called “niche”. Drosophila melanogaster is a powerful model organism to decipher the mechanisms controlling hematopoiesis,… read more here.
Keywords: drosophila; response; blood; niche ... See more keywords
Headcase is a Repressor of Lamellocyte Fate in Drosophila melanogaster
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.3390/genes10030173
Abstract: Due to the evolutionary conservation of the regulation of hematopoiesis, Drosophila provides an excellent model organism to study blood cell differentiation and hematopoietic stem cell (HSC) maintenance. The larvae of Drosophila melanogaster respond to immune… read more here.
Keywords: drosophila; drosophila melanogaster; fate; blood ... See more keywords