Albumin-Hitchhiking Drug Delivery to Tumor-draining Lymph Nodes Precisely Boosts Tumor-Specific Immunity through Autophagy Modulation of Immune Cells.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211055
Abstract: Tumor-draining lymph nodes (TDLNs) are the first sites where tumor components reach and dendritic cells (DCs) present tumor-associated antigens to T cells. DCs rely on autophagy to process tumor antigens into epitope peptides to form… read more here.
Keywords: draining lymph; immunity; tumor draining; lymph nodes ... See more keywords
Targeting L-Selectin Lymphocytes to Deliver Immunosuppressive Drug in Lymph Nodes for Durable Multiple Sclerosis Treatment.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300738
Abstract: Inflammation induced by autoreactive CD4+ T lymphocytes is a major factor in the pathogenesis of multiple sclerosis (MS). Immunosuppressive drugs, such as FTY720, are subsequently developed to prevent the migration of CD4+ T lymphocytes to… read more here.
Keywords: selectin; immunosuppressive drugs; lymph nodes; treatment ... See more keywords
Staging of pancreatic cancer based on the number of positive lymph nodes
Sign Up to like & getrecommendations! Published in 2017 at "British Journal of Surgery"
DOI: 10.1002/bjs.10472
Abstract: The International Study Group on Pancreatic Surgery has stated that at least 12 lymph nodes should be evaluated for staging of pancreatic cancer. The aim of this population‐based study was to evaluate whether the number… read more here.
Keywords: staging pancreatic; lymph nodes; number positive; pancreatic cancer ... See more keywords
Excision of mesenteric lymph nodes alters gut microbiota and impairs social dominance in adult mice.
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DOI: 10.1002/brb3.3053
Abstract: INTRODUCTION Mesenteric lymph nodes (MLNs) are central in immune anatomy. MLNs are associated with the composition of gut microbiota, affecting the central system and immune system. Gut microbiota was found to differ among individuals of… read more here.
Keywords: gut microbiota; social dominance; lymph nodes; dominance ... See more keywords
Anatomical analysis of gastric lymph nodes in cancer–free individuals
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Anatomy"
DOI: 10.1002/ca.23241
Abstract: Lymphadenectomy is a crucial part of the surgical therapy for gastric cancer. The number of normal lymph nodes could indicate the number of nodes that need to be retrieved during the procedure. The aim of… read more here.
Keywords: gastric cancer; lymph; number lymph; lymph nodes ... See more keywords
A deep learning nomogram kit for predicting metastatic lymph nodes in rectal cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3490
Abstract: Preoperative diagnoses of metastatic lymph nodes (LNs) by the most advanced deep learning technology of Faster Region‐based Convolutional Neural Network (Faster R‐CNN) have not yet been reported. read more here.
Keywords: lymph nodes; metastatic lymph; deep learning; learning nomogram ... See more keywords
Ultrasound‐guided FNA cytology of groin lymph nodes improves the management of squamous cell carcinoma of the vulva: Results from a comparative cytohistological study
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Cytopathology"
DOI: 10.1002/cncy.22154
Abstract: Lymph node metastases represent the most important negative prognostic predictor in vulvar carcinoma. Therefore, an accurate preoperative assessment of suspicious lymph nodes would be fundamental for a personalized therapy. The aim of this article was… read more here.
Keywords: carcinoma; lymph nodes; lymph; ultrasound guided ... See more keywords
The prognostic value of tumor–stroma ratio in tumor‐positive axillary lymph nodes of breast cancer patients
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31658
Abstract: The tumor–stroma ratio (TSR) has previously been found to be a strong prognostic parameter in primary breast cancer tumors. Since the presence of tumor cells in lymph nodes is important for clinical decision making, the… read more here.
Keywords: tumor positive; lymph nodes; lymph; cancer ... See more keywords
A new definition about the relationship of intercellular fluid in the brain with the mandibular and parotid lymph nodes.
Sign Up to like & getrecommendations! Published in 2021 at "Microscopy research and technique"
DOI: 10.1002/jemt.23898
Abstract: This study was carried out to reveal the relationship of the brain with both the mandibular lymph node (MLN) and parotid lymph node (PLN) by the hyperspectral fluorescence imaging techniques of Qdot 800 (QD) nanoparticles… read more here.
Keywords: lymph nodes; lymph; parotid lymph; brain ... See more keywords
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12197
Abstract: Abstract Tumour‐draining lymph nodes (LNs) undergo massive remodelling including expansion of the lymphatic sinuses, a process that has been linked to lymphatic metastasis by creation of a pre‐metastatic niche. However, the signals leading to these… read more here.
Keywords: derived extracellular; extracellular vesicles; vesicles mediate; draining lymph ... See more keywords
Antiretroviral drug exposure in lymph nodes is heterogeneous and drug dependent
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the International AIDS Society"
DOI: 10.1002/jia2.25895
Abstract: HIV reservoirs and infected cells may persist in tissues with low concentrations of antiretrovirals (ARVs). Traditional pharmacology methods cannot assess variability in ARV concentrations within morphologically complex tissues, such as lymph nodes (LNs). We evaluated… read more here.
Keywords: drug exposure; nodes heterogeneous; drug; exposure lymph ... See more keywords