Pulmonary Langerhans cell histiocystosis (PLCH) and lymphangioleiomyomatosis (LAM) have circulating cells with loss of heterozygosity of the TSC2 gene.
Sign Up to like & getrecommendations! Published in 2022 at "Chest"
DOI: 10.1016/j.chest.2022.02.032
Abstract: BACKGROUND Lymphangioleiomyomatosis (LAM) and pulmonary Langerhans Cell Histiocytosis (PLCH) are cystic lung diseases in which a neoplastic cell is believed to be responsible for disease pathogenesis. The neoplastic LAM cell has mutations in the Tuberous… read more here.
Keywords: tsc2 loh; cell; lymphangioleiomyomatosis lam; plch ... See more keywords
Abstract 1230: The pre-metastatic niche establishment through the induction of the epithelial-to-mesenchymal transition by circulating exosomes in lymphangioleiomyomatosis (LAM): implication of the complement cascade
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DOI: 10.1158/1538-7445.am2023-1230
Abstract: Exosomes are a class of extra cellular vesicles (EVs), with a multi vesicular endosomal origin, that are released by all cell types, with sizes ranging from 30-150nm and a lipid bilayer membrane. They have been… read more here.
Keywords: lymphangioleiomyomatosis lam; derived exosomes; pre metastatic; niche establishment ... See more keywords
Off-Pump Coronary Artery Bypass Grafting in a Patient with Lymphangioleiomyomatosis (LAM): Navigating the Perioperative Challenges
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DOI: 10.4103/aca.aca_168_21
Abstract: To The Editor, Lymphangioleiomyomatosis (LAM) is a chronic, progressive, and complex disease that almost always affects women. Women of childbearing age are frequently affected, albeit it is seen in the post‐menopausal age group as well.… read more here.
Keywords: lymphangioleiomyomatosis lam; lam; coronary artery; artery bypass ... See more keywords