Autophagy-dependent expression of osteopontin and its downstream Stat3 signaling contributes to lymphatic malformation progression to lymphangiosarcoma.
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DOI: 10.1080/15548627.2023.2213527
Abstract: Lymphatic malformation (LM) is a vascular anomaly from lymphatic endothelial cells (ECs), and a fraction of the patients could progress to the deadly malignant lymphangiosarcoma (LAS). Using genetic tools to delete an essential autophagy gene… read more here.
Keywords: progression; stat3 signaling; lymphatic malformation; lymphangiosarcoma ... See more keywords