Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion
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DOI: 10.1161/circresaha.121.320565
Abstract: Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated calcium modulator 1)-mediated mechanotransduction pathway that triggers lymphatic sprouting through Notch… read more here.
Keywords: lymphatic sprouting; regulated mechanotransduction; lymphatic expansion; mechanotransduction ... See more keywords