Clinical application of molecular genetics in lymphatic malformations
Sign Up to like & getrecommendations! Published in 2019 at "Laryngoscope Investigative Otolaryngology"
DOI: 10.1002/lio2.241
Abstract: To describe the clinical presentation of lymphatic malformations (LM) and genotypically associated disorders and to summarize the recent literature regarding the genetic etiology of LM and provide a biologic correlation to medical and surgical management. read more here.
Keywords: lymphatic malformations; genetics; application molecular; molecular genetics ... See more keywords
Cervical lymphatic malformations: Prenatal characteristics and ex utero intrapartum treatment
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DOI: 10.1002/pd.5428
Abstract: The ex utero intrapartum treatment (EXIT) is utilized to transition fetuses with prenatally diagnosed airway obstruction to postnatal life. We describe the unique clinical course, diagnosis, treatment, and outcomes of patients with cervical lymphatic malformation… read more here.
Keywords: lymphatic malformations; cervical lymphatic; treatment; intrapartum treatment ... See more keywords
Single center experience with intralesional bleomycin sclerotherapy for lymphatic malformations
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DOI: 10.1007/s11604-017-0672-5
Abstract: PurposeThe purpose of our study was to evaluate the efficacy of percutaneous sclerotherapy using bleomycin in treatment of lymphatic malformations.MethodsBetween January 2009 and January 2013, ten patients with lymphatic malformations who were admitted to the… read more here.
Keywords: lymphatic malformations; treatment; sclerotherapy; radiology ... See more keywords
Cervical lymphatic malformations: Prenatal imaging characteristics and neonatal outcomes of ex‐ utero intrapartum treatment: 216
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Obstetrics and Gynecology"
DOI: 10.1016/j.ajog.2018.11.237
Abstract: 216 Cervical lymphatic malformations: Prenatal imaging characteristics and neonatal outcomes of exutero intrapartum treatment Kelsey A. Stewart, Hadi Erfani, Sohum C. Shah, Ava Y. Jang, Elizabeth S. Kravitz, Ahmed A. Nassr, Jimmy Espinoza, Timothy C.… read more here.
Keywords: lymphatic malformations; cervical lymphatic; intrapartum treatment; malformations prenatal ... See more keywords
Endoscopy-assisted, transoral submucosal coblation for pediatric retropharyngeal lymphatic malformations.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pediatric otorhinolaryngology"
DOI: 10.1016/j.ijporl.2020.110074
Abstract: OBJECTIVE Retropharyngeal lymphatic malformations (LMs) are uncommon congenital anomalies. Open surgery, sclerotherapy and various pharmaceutical agents have been described to manage these lesions. However, when such lesions involve the retropharyngeal space with evidence of airway… read more here.
Keywords: coblation; lymphatic malformations; retropharyngeal lymphatic; assisted transoral ... See more keywords
Assessment of PI3K/AKT and MAPK/ERK pathways activation in oral lymphatic malformations.
Sign Up to like & getrecommendations! Published in 2021 at "Oral surgery, oral medicine, oral pathology and oral radiology"
DOI: 10.1016/j.oooo.2021.08.018
Abstract: OBJECTIVE Lymphatic malformations are characterized by the overgrowth of lymphatic vessels during development. Activation of PI3K/AKT and MAPK/ERK signaling pathways occur in isolated lymphatic malformation and in those associated with syndromes such as CLOVES and… read more here.
Keywords: lymphatic malformations; pi3k akt; akt mapk; activation ... See more keywords
Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation
Sign Up to like & getrecommendations! Published in 2020 at "Nature Communications"
DOI: 10.1038/s41467-020-16496-y
Abstract: Lymphatic malformations (LMs) are debilitating vascular anomalies presenting with large cysts (macrocystic) or lesions that infiltrate tissues (microcystic). Cellular mechanisms underlying LM pathology are poorly understood. Here we show that the somatic PIK3CAH1047R mutation, resulting… read more here.
Keywords: lymphatic malformations; pik3ca mutation; blockade vegf; vegf signaling ... See more keywords
An 8-year population description from a national treatment centre on lymphatic malformations
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DOI: 10.1080/2000656x.2016.1254092
Abstract: Abstract Introduction: Lymphatic malformations are rare developmental non-malignant abnormalities that present as masses consisting of abnormal growth of fluid filled channels or spaces in the skin or deep tissue that result in abnormalities of lymphatic… read more here.
Keywords: year population; lymphatic malformations; population description; treatment ... See more keywords
Cytological and Biochemical Analyses of Lymphatic Fluid from Patients with Lymphatic Malformations.
Sign Up to like & getrecommendations! Published in 2023 at "Lymphatic research and biology"
DOI: 10.1089/lrb.2021.0068
Abstract: Background: Intracystic hemorrhage from lymphangiomas is a common phenomenon in lymphatic malformations (LMs); however, little is known about the associated compositional changes in the lymphatic fluid. Materials and Methods: We prospectively collected lymphatic fluid from… read more here.
Keywords: lymphatic fluid; biochemical analyses; analyses lymphatic; fluid ... See more keywords
Sirolimus in the Treatment of Microcystic Lymphatic Malformations: A Systematic Review.
Sign Up to like & getrecommendations! Published in 2022 at "Lymphatic research and biology"
DOI: 10.1089/lrb.2021.0103
Abstract: Background: Genetic alterations in lymphatic development can lead to microcystic lymphatic malformations (micro LMs). LMs can have both microcystic and macrocytic components or be exclusively one or the other. LMs can result in serious, sometimes… read more here.
Keywords: sirolimus; systematic review; micro; lymphatic malformations ... See more keywords
National Characteristics of Lymphatic Malformations in Children: Inpatient Estimates and Trends in the United States, 2000 to 2009
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DOI: 10.1097/mph.0000000000001078
Abstract: With ever increasing demands to manage finite resources for health care utilization, we performed an investigation to identify inpatient clinical characteristics and trends in children with lymphatic malformations using the Kids’ Inpatient Database, years 2000… read more here.
Keywords: national characteristics; 2000 2009; lymphatic malformations; united states ... See more keywords