Nectin-4 promotes lymphangiogenesis and lymphatic metastasis in breast cancer by regulating CXCR4- LYVE1 axis.
Sign Up to like & getrecommendations! Published in 2021 at "Vascular pharmacology"
DOI: 10.1016/j.vph.2021.106865
Abstract: Tumor-induced lymphangiogenesis promotes tumor progression by generating new lymphatic vessels that helps in tumor dissemination to regional lymph nodes and distant sites. Recently, the role of Nectin-4 in cancer metastasis and angiogenesis has been studied,… read more here.
Keywords: lymphatic metastasis; lymphangiogenesis lymphatic; breast cancer; cancer ... See more keywords
Aminopeptidase N Activatable Nanoprobe for Tracking Lymphatic Metastasis and Guiding Tumor Resection Surgery via Optoacoustic/NIR-II Fluorescence Dual-Mode Imaging.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c01241
Abstract: Lymphatic metastasis is a crucial mechanism by which the cancer cells break away from the primary (original) tumor and travel to the closest regional lymph node(s) and ultimately to other organs or parts of the… read more here.
Keywords: resection surgery; lymphatic metastasis; tumor; nanoprobe ... See more keywords
Charge Reversal Polypyrrole Nanocomplex-Mediated Gene Delivery and Photothermal Therapy for Effectively Treating Papillary Thyroid Cancer and Inhibiting Lymphatic Metastasis.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.1c25179
Abstract: As a traditional treatment for papillary thyroid cancer (PTC), surgical resection of diseased tissues often brings lots of inconveniences to patients, and the tumor recurrence and metastasis are difficult to avoid. Herein, we developed a… read more here.
Keywords: lymphatic metastasis; therapy; metastasis; gene ... See more keywords
A core-satellite micellar system against primary tumors and their lymphatic metastasis through modulation of fatty acid metabolism blockade and tumor-associated macrophages.
Sign Up to like & getrecommendations! Published in 2023 at "Nanoscale"
DOI: 10.1039/d2nr04693h
Abstract: Lymph nodes (LNs) are the initial sanctuary of various metastatic tumor cells, and thus a precise lymphatic drug delivery strategy is necessary for the effective inhibition of metastasis. However, the complex biological barriers have restrained… read more here.
Keywords: metastasis; core satellite; micellar system; lymphatic metastasis ... See more keywords
Gene signature characteristic of elevated stromal infiltration and activation is associated with increased risk of hematogenous and lymphatic metastasis in serous ovarian cancer
Sign Up to like & getrecommendations! Published in 2019 at "BMC Cancer"
DOI: 10.1186/s12885-019-6470-y
Abstract: BackgroundThe clinical significance of hematogenous and lymphatic metastasis in ovarian cancer has been increasingly addressed, as it plays an imperative role in the formation of both intraperitoneal and distant metastases. Our objective is to identify… read more here.
Keywords: serous ovarian; lymphatic metastasis; ovarian cancer; cancer ... See more keywords
ASO Author Reflections: Lymphatic Metastasis of Small Bowel Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Surgical Oncology"
DOI: 10.1245/s10434-018-7013-5
Abstract: Since lymphatic metastasis is very common in patients with small bowel (jejunoileal) neuroendocrine tumors (SBNETs), treatment with lymphadenectomy is recommended by guidelines whenever it is available. However, what is less well known is how to… read more here.
Keywords: small bowel; author reflections; lymphatic metastasis; metastasis ... See more keywords
Long non-coding RNA MFSD4A-AS1 promotes lymphangiogenesis and lymphatic metastasis of papillary thyroid cancer
Sign Up to like & getrecommendations! Published in 2023 at "Endocrine-Related Cancer"
DOI: 10.1530/erc-22-0221
Abstract: Lymphatic metastasis is the leading cause responsible for recurrence and progression in papillary thyroid cancer (PTC), where dysregulation of long non-coding RNAs (lncRNAs) has been extensively demonstrated to be implicated. However, the specific lymphatic node… read more here.
Keywords: ptc; lymphatic metastasis; cancer; mfsd4a as1 ... See more keywords
Effect of 3q oncogenes SEC62 and SOX2 on lymphatic metastasis and clinical outcome of head and neck squamous cell carcinomas
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.13986
Abstract: Chromosome 3q26 amplification represents a frequent alteration in head and neck squamous cell carcinomas (HNSCCs). Overexpression of 3q26 encoded genes SEC62 and SOX2 was detected in various cancers, including HNSCCs, indicating their potential function as… read more here.
Keywords: sox2 expression; lymphatic metastasis; sec62 sox2; cell ... See more keywords
Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rho GTPase in esophageal squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.14087
Abstract: To establish treatments to improve the prognosis of cancer patients, it is necessary to find new targets to control metastasis. We found that expression of FilaminC (FLNC), a member of the actin binding and cross-linking… read more here.
Keywords: lymphatic invasion; lymphatic metastasis; invasion lymphatic; metastasis ... See more keywords
LncRNA DANCR regulates lymphatic metastasis of bladder cancer via the miR-335/VEGF-C axis.
Sign Up to like & getrecommendations! Published in 2021 at "Translational andrology and urology"
DOI: 10.21037/tau-21-226
Abstract: Background Substantial evidence indicate that long non-coding RNA (lncRNA) and microRNA (miRNA) act as key role in bladder cancer. Differentiation antagonistic ncRNA (DANCR) could be used as a biomarker in the occurrence and development of… read more here.
Keywords: bladder cancer; lymphatic metastasis; 335 vegf; cancer ... See more keywords
Seven Genes Associated With Lymphatic Metastasis in Thyroid Cancer That Is Linked to Tumor Immune Cell Infiltration
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2021.756246
Abstract: Objective Since there are few studies exploring genes associated with lymphatic metastasis of thyroid carcinoma (THCA), this study was conducted to explore genes associated with lymphatic metastasis of THCA and to investigate the relationship with… read more here.
Keywords: genes associated; lymphatic metastasis; metastasis; associated lymphatic ... See more keywords