TGFBIp mediates lymphatic sprouting in corneal lymphangiogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.14633
Abstract: Corneal lymphangiogenesis plays a key role in diverse pathological conditions of the eye. Here, we demonstrate that a versatile extracellular matrix protein, transforming growth factor‐β induced protein (TGFBIp), promotes lymphatic sprouting in corneal lymphangiogenesis. TGFBIp… read more here.
Keywords: lymphangiogenesis; corneal lymphangiogenesis; sprouting corneal; tgfbip ... See more keywords
Piezo1-Regulated Mechanotransduction Controls Flow-Activated Lymphatic Expansion
Sign Up to like & getrecommendations! Published in 2022 at "Circulation Research"
DOI: 10.1161/circresaha.121.320565
Abstract: Background: Mutations in PIEZO1 (Piezo type mechanosensitive ion channel component 1) cause human lymphatic malformations. We have previously uncovered an ORAI1 (ORAI calcium release-activated calcium modulator 1)-mediated mechanotransduction pathway that triggers lymphatic sprouting through Notch… read more here.
Keywords: lymphatic sprouting; regulated mechanotransduction; lymphatic expansion; mechanotransduction ... See more keywords