Postnatal development of lymphatic vasculature in the brain meninges
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Dynamics"
DOI: 10.1002/dvdy.24624
Abstract: Background: Traditionally, the central nervous system (CNS) has been viewed as an immune‐privileged environment with no lymphatic vessels. This view was partially overturned by the discovery of lymphatic vessels in the dural membrane that surrounds… read more here.
Keywords: dural lymphatic; lymphatic vasculature; lymphatic vessels; brain ... See more keywords
The lymphatic vasculature revisited-new developments in the zebrafish.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in cell biology"
DOI: 10.1016/bs.mcb.2016.11.001
Abstract: The lymphatic system is lined by endothelial cells and part of the vasculature. It is essential for tissue fluid homeostasis, absorption of dietary fats, and immune surveillance in vertebrates. Misregulation of lymphatic vessel formation and… read more here.
Keywords: vasculature; revisited new; lymphatic vasculature; vasculature revisited ... See more keywords
Characterization of dural sinus-associated lymphatic vasculature in human Alzheimer’s dementia subjects
Sign Up to like & getrecommendations! Published in 2018 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.07.020
Abstract: Recent reports describing lymphatic vasculature in the meninges have challenged the traditional understanding of interstitial solute clearance from the central nervous system, although the significance of this finding in human neurological disease remains unclear. To… read more here.
Keywords: vasculature; alzheimer; lymphatic vasculature; vasculature human ... See more keywords
The Lymphatic Vasculature: Its Role in Adipose Metabolism and Obesity.
Sign Up to like & getrecommendations! Published in 2017 at "Cell metabolism"
DOI: 10.1016/j.cmet.2017.07.020
Abstract: Obesity is a key risk factor for metabolic and cardiovascular diseases, and although we understand the mechanisms regulating weight and energy balance, the causes of some forms of obesity remain enigmatic. Despite the well-established connections… read more here.
Keywords: obesity; lymphatic vasculature; adipose metabolism; adipose tissue ... See more keywords
Lymphatic vasculature in human dural superior sagittal sinus: Implications for neurodegenerative proteinopathies
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2017.11.001
Abstract: Recent reports have characterized functional lymphatic vessels, which drain both fluid and immune cells from the CSF to the deep cervical lymph nodes, lining the dural sinuses in mice. If conserved in the human brain… read more here.
Keywords: neurodegenerative proteinopathies; sagittal sinus; lymphatic vasculature; vasculature human ... See more keywords
Meningeal Lymphatic vasculature in health and disease
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000711
Abstract: Purpose of review The recent (re)discovery of the meningeal lymphatic has brought a new player in brain neurophysiology. This review highlights the state of the current research on the meningeal lymphatic vasculature, from its specific… read more here.
Keywords: vasculature health; lymphatic vasculature; health disease; meningeal lymphatic ... See more keywords
Molecular Mechanisms Driving Lymphedema and Other Lymphatic Anomalies.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041272
Abstract: Lymphatic vasculature regulates fluid homeostasis by absorbing interstitial fluid and returning it to blood. Lymphatic vasculature is also critical for lipid absorption and inflammatory response. Lymphatic vasculature is composed of lymphatic capillaries, collecting lymphatic vessels,… read more here.
Keywords: lymphatic vasculature; driving lymphedema; mechanisms driving; molecular mechanisms ... See more keywords
Apelin modulates pathological remodeling of lymphatic endothelium after myocardial infarction.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.93887
Abstract: Lymphatic endothelium serves as a barrier to control fluid balance and immune cell trafficking to maintain tissue homeostasis. Long-term alteration of lymphatic vasculature promotes edema and fibrosis, which is an aggravating factor in the onset… read more here.
Keywords: apelin; lymphatic vasculature; myocardial infarction; lymphatic endothelium ... See more keywords
The lymphatic vasculature in lung function and respiratory disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2023.1118583
Abstract: The lymphatic vasculature maintains tissue homeostasis via fluid drainage in the form of lymph and immune surveillance due to migration of leukocytes through the lymphatics to the draining lymph nodes. Lymphatic endothelial cells (LECs) form… read more here.
Keywords: lymphatic vasculature; function; disease; lung ... See more keywords
Single and combined impacts of irradiation and surgery on lymphatic vasculature and fibrosis associated to secondary lymphedema
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1016138
Abstract: Lymphedema (LD) refers to a condition of lymphatic dysfunction associated with excessive fluid accumulation, fibroadipose tissue deposition and swelling. In industrialized countries, LD development mainly results from a local disruption of the lymphatic network by… read more here.
Keywords: lymphatic vasculature; surgery; lymphedema; deposition ... See more keywords
VE-Cadherin and Vesicles Differentially Regulate Lymphatic Vascular Permeability to Solutes of Various Sizes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2021.687563
Abstract: Lymphatic vascular permeability prevents lymph leakage that is associated with lymphedema, lymphatic malformations, obesity, and inflammation. However, the molecular control of lymphatic permeability remains poorly understood. Recent studies have suggested that adherens junctions and vesicle… read more here.
Keywords: kda dextran; permeability; lymphatic vasculature; lymphatic vascular ... See more keywords