LINC00657 activates PD-L1 to promote osteosarcoma metastasis via miR-106a.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.29574
Abstract: Osteosarcoma (OS) cells are one of the primary cancer-related causes of death around the world. Long noncoding RNAs are key for OS progression; however, the detailed molecular mechanism remains unknown. LINC00657, miR-106a, and programmed death… read more here.
Keywords: linc00657; metastasis; vessel formation; linc00657 activates ... See more keywords
Improvement of the efficacy of vascularized lymph node transfer for lower‐extremity lymphedema via a prefabricated lympho‐venous shunt through lymphaticovenular anastomosis between the efferent lymphatic vessel and small vein in the elevated vascularized lymph node
Sign Up to like & getrecommendations! Published in 2018 at "Microsurgery"
DOI: 10.1002/micr.30234
Abstract: Following vascularized lymph node (VLN) transfer (VLNT), the VLN may be at a risk for sclerosis because of efferent lymphatic vessel obstruction. We developed a new technique to prevent VLN sclerosis via a prefabricated lympho‐venous… read more here.
Keywords: efferent lymphatic; via prefabricated; vascularized lymph; lymph node ... See more keywords
Octopus anastomosis: selection of anastomotic configuration in lymphaticovenular anastomosis according to vessels’ conditions
Sign Up to like & getrecommendations! Published in 2021 at "Breast Cancer Research and Treatment"
DOI: 10.1007/s10549-021-06157-z
Abstract: We read with great interest the article entitled “Outcomes Following Lymphaticovenous Anastomosis (LVA) for 100 Cases of Lymphedema: Results over 24-months Follow-up” by Qiu et al. [1]. LVA performed by authors did not show a… read more here.
Keywords: lymphatic vessels; anastomosis; selection anastomotic; lymphatic vessel ... See more keywords
Human organotypic lymphatic vessel model elucidates microenvironment-dependent signaling and barrier function.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119225
Abstract: The lymphatic system is an active player in the pathogenesis of several human diseases, including lymphedema and cancer. Relevant models are needed to advance our understanding of lymphatic biology in disease progression to improve therapy… read more here.
Keywords: system; biology; lymphatic vessels; function ... See more keywords
Synthetic hydrogels engineered to promote collecting lymphatic vessel sprouting.
Sign Up to like & getrecommendations! Published in 2022 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2022.121483
Abstract: The lymphatic vasculature is an essential component of the body's circulation providing a network of vessels to return fluid and proteins from the tissue space to the blood, to facilitate immune ce-ll and antigen transport… read more here.
Keywords: lymphatic vessel; engineered promote; hydrogels engineered; vessel ... See more keywords
Isolated lymphatic vessel lumen perfusion system for assessing nanomaterial movements and nanomaterial-induced responses in lymphatic vessels
Sign Up to like & getrecommendations! Published in 2021 at "Nano Today"
DOI: 10.1016/j.nantod.2020.101018
Abstract: Abstract Nanomaterials have recently been investigated extensively for a wide variety of biological applications, including drug delivery, bioimaging, and regenerative medicine. However, they have found little clinical use because of the lack of an established… read more here.
Keywords: isolated lymphatic; system; perfusion system; lymphatic vessels ... See more keywords
Specific immune cell and lymphatic vessel signatures identified by image analysis in renal cancer
Sign Up to like & getrecommendations! Published in 2019 at "Modern Pathology"
DOI: 10.1038/s41379-019-0214-z
Abstract: Anti-angiogenic therapy and immune checkpoint inhibition are novel treatment strategies for patients with renal cell carcinoma. Various components and structures of the tumor microenvironment are potential predictive biomarkers and also attractive treatment targets. Macrophages, tumor… read more here.
Keywords: immune; cell; vessel; image analysis ... See more keywords
Cardiac macrophages regulate lymphatic vessel growth during heart development
Sign Up to like & getrecommendations! Published in 2021 at "Nature Reviews Cardiology"
DOI: 10.1038/s41569-021-00519-2
Abstract: Tissue-resident macrophages form direct interactions with lymphatic endothelial cells and regulate the growth and sprouting of lymphatic vessels during development of the mammalian cardiac vasculature. read more here.
Keywords: cardiac macrophages; regulate lymphatic; development; growth ... See more keywords
Lymphatic vessel density is associated with CD8+ T cell infiltration and immunosuppressive factors in human melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1462878
Abstract: ABSTRACT Increased density of tumor-associated lymphatic vessels correlates with poor patient survival in melanoma and other cancers, yet lymphatic drainage is essential for initiating an immune response. Here we asked whether and how lymphatic vessel… read more here.
Keywords: cell infiltration; vessel density; cell; lymphatic vessel ... See more keywords
Prognostic significance of lymphatic vessel invasion diagnosed by D2-40 in Chinese invasive breast cancers
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008490
Abstract: Abstract Lymphatic vessel invasion (LVI) is promising in determining prognosis and treatment strategies, but the application of LVI as a histopathological criterion in breast cancer patients especially those of different subgroups is controversial. This research… read more here.
Keywords: breast; luminal like; lvi; lymph node ... See more keywords
Lymphatic vessel involvement in primary cutaneous B-cell lymphoma: A common finding?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cutaneous pathology"
DOI: 10.1111/cup.14440
Abstract: BACKGROUND Cutaneous B-cell lymphoma (CBCL) is part of dermatopathological routine diagnostics. However, in contrast to cutaneous T-cell lymphomas, there are only a few studies on the prevalence and possible clinical impact of lymphatic vessel involvement.… read more here.
Keywords: lymphatic vessel; vessel involvement; cutaneous cell; involvement ... See more keywords