Overexpression of Lymphocyte Antigen 6 Complex, Locus E in Gastric Cancer Promotes Cancer Cell Growth and Metastasis
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DOI: 10.1159/000487453
Abstract: Background/Aims: Lymphocyte antigen 6 complex, locus E (LY6E) is a member of the lymphostromal cell membrane Ly6 superfamily protein. The present study investigated the clinical significance and potential biological function of LY6E in gastric cancer… read more here.
Keywords: expression; complex locus; lymphocyte antigen; cancer ... See more keywords
Soluble cytotoxic T-lymphocyte antigen 4: a favorable predictor in malignant tumors after therapy
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DOI: 10.2147/ott.s128451
Abstract: Purpose Soluble cytotoxic T-lymphocyte antigen 4 (sCTLA-4), one of the isoforms of CTLA-4, was discovered to be critical in downregulating the negative signal of CTLA-4 in T-cell responses. Contrary to the classical immunosuppressive effect of… read more here.
Keywords: soluble cytotoxic; cytotoxic lymphocyte; lymphocyte antigen;
The Role of Cytotoxic T-Lymphocyte Antigen 4 in the Pathogenesis of Multiple Sclerosis
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DOI: 10.3390/genes13081319
Abstract: Multiple sclerosis (MS) is an autoimmune neurodegenerative disorder of the central nervous system that presents heterogeneous clinical manifestations and course. It has been shown that different immune checkpoints, including Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4), can… read more here.
Keywords: ctla; multiple sclerosis; lymphocyte antigen; cytotoxic lymphocyte ... See more keywords