High lymphocyte counts before antithymocyte globulin administration predict acute graft-versus-host disease
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Hematology"
DOI: 10.1007/s00277-020-04347-1
Abstract: Antithymocyte globulin (ATG) reduces severe acute and chronic graft-versus-host disease (GVHD) in allogeneic peripheral blood stem cell transplantation (PBSCT). However, risk factors for severe acute GVHD in PBSCT using ATG remain to be determined. We… read more here.
Keywords: lymphocyte counts; alc atg; versus host; host disease ... See more keywords
Exposure-Response Analyses of the Effects of Venetoclax, a Selective BCL-2 Inhibitor, on B-Lymphocyte and Total Lymphocyte Counts in Women with Systemic Lupus Erythematosus
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DOI: 10.1007/s40262-019-00818-5
Abstract: Background Venetoclax is a selective inhibitor of B-cell lymphoma-2, which plays a role in the development of various autoimmune diseases including systemic lupus erythematosus. The aim of these analyses was to quantify the exposure-response relationship… read more here.
Keywords: lymphocyte counts; total lymphocyte; lupus erythematosus; systemic lupus ... See more keywords
Effect of Ponesimod Exposure on Total Lymphocyte Dynamics in Patients with Multiple Sclerosis
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DOI: 10.1007/s40262-021-01019-9
Abstract: The aim of this study was to characterize the relationship between ponesimod plasma concentrations and the temporal evolution of lymphocyte counts in multiple sclerosis (MS) patients. Population pharmacokinetic (PK) and PK/pharmacodynamic (PD) models were developed… read more here.
Keywords: lymphocyte counts; ponesimod; total lymphocyte; clinically relevant ... See more keywords
The c.305del3 in IL‐2 gene in Homonoidea theoretically affects IL‐2/IL‐2R&agr; interaction as well as lymphocyte homeostasis
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DOI: 10.1016/j.cyto.2017.11.011
Abstract: HighlightsIL‐2 structural analysis among primates showed c.305del3 in Hominoidea superfamily.The above mentioned deletion led to weaker interaction of human IL‐2 to its receptor relative to ancestral IL‐2.This deletion in IL‐2 showed an evolutionary effect on… read more here.
Keywords: homeostasis; lymphocyte counts; gene homonoidea; deletion ... See more keywords
Dynamic changes of lymphocyte counts in adult patients with severe pandemic H1N1 influenza A
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DOI: 10.1016/j.jiph.2019.05.017
Abstract: Abstract Background Lymphopenia has been observed in severe pandemic influenza A/H1N1 in developed countries. However, data from developing countries are rare and dynamic change of lymphocyte counts in severe pandemic influenza A/H1N1 is scarcely reported.… read more here.
Keywords: h1n1; lymphocyte counts; influenza h1n1; pandemic influenza ... See more keywords
Clinical Analysis of 25 Novel Coronavirus Infections in Children.
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DOI: 10.1097/inf.0000000000002740
Abstract: BACKGROUND To describe the characteristics of clinical manifestations of children with 2019 novel coronavirus (2019-nCoV) infection in Chongqing. METHODS All 25 children with laboratory-confirmed 2019-nCoV infection by real-time reverse transcription-PCR (RNA-PCR) were admitted from the… read more here.
Keywords: ncov infection; 2019 ncov; lymphocyte counts; novel coronavirus ... See more keywords
Immune cell function assay and T lymphocyte counts lack association with rejection or infection in pediatric heart transplant recipients
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DOI: 10.1111/ctr.14858
Abstract: Immune cell function assay (ICFA) and CD3 lymphocyte counts have been considered to be useful in discerning the overall intensity of immunosuppression in pediatric orthotopic heart transplant (OHT) recipients. read more here.
Keywords: heart transplant; immune cell; cell function; lymphocyte counts ... See more keywords
The Independent Association of TSH and Free Triiodothyronine Levels With Lymphocyte Counts Among COVID-19 Patients
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DOI: 10.3389/fendo.2021.774346
Abstract: Background Both lymphopenia and thyroid dysfunction are commonly observed among COVID-19 patients. Whether thyroid function independently correlates with lymphocyte counts (LYM) remains to be elucidated. Methods We included consecutive adults without known thyroid disorder admitted… read more here.
Keywords: covid patients; lymphocyte counts; tsh free; among covid ... See more keywords
SARS-CoV-2 Dysregulates Neutrophil Degranulation and Reduces Lymphocyte Counts
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DOI: 10.3390/biomedicines10020382
Abstract: SARS-CoV-2, the virus that causes COVID-19, has given rise to one of the largest pandemics, affecting millions worldwide. High neutrophil-to-lymphocyte ratios have been identified as an important correlate to poor recovery rates in severe COVID-19… read more here.
Keywords: cov dysregulates; dysregulates neutrophil; lymphocyte counts; neutrophil degranulation ... See more keywords
Low Absolute Lymphocyte Counts in the Peripheral Blood Predict Inferior Survival and Improve the International Prognostic Index in Testicular Diffuse Large B-Cell Lymphoma
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DOI: 10.3390/cancers12071967
Abstract: Low absolute lymphocyte counts (ALC) and high absolute monocyte counts (AMC) are associated with poor survival in patients with diffuse large B-cell lymphoma (DLBCL). We studied the prognostic impact of the ALC and AMC in… read more here.
Keywords: lymphocyte counts; low absolute; large cell; absolute lymphocyte ... See more keywords