The HDAC7–TET2 epigenetic axis is essential during early B lymphocyte development
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac619
Abstract: Abstract Correct B cell identity at each stage of cellular differentiation during B lymphocyte development is critically dependent on a tightly controlled epigenomic landscape. We previously identified HDAC7 as an essential regulator of early B… read more here.
Keywords: hdac7 tet2; development; cell; lymphocyte development ... See more keywords
Regulation of Early Lymphocyte Development via mRNA Decay Catalyzed by the CCR4-NOT Complex
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.715675
Abstract: Development of lymphocytes is precisely regulated by various mechanisms. In addition to transcriptional rates, post-transcriptional regulation of mRNA abundance contributes to differentiation of lymphocytes. mRNA decay is a post-transcriptional mechanism controlling mRNA abundance. The carbon… read more here.
Keywords: ccr4; lymphocyte development; mrna decay; ccr4 complex ... See more keywords
Transcriptional Regulation of Early T-Lymphocyte Development in Thymus
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.884569
Abstract: T-lymphocytes play crucial roles for maintaining immune homeostasis by fighting against various pathogenic microorganisms and establishing self-antigen tolerance. They will go through several stages and checkpoints in the thymus from progenitors to mature T cells,… read more here.
Keywords: cd4 cd8; early lymphocyte; regulation early; development ... See more keywords