Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Immunology"
DOI: 10.1038/s41423-020-00625-0
Abstract: A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by commensal bacteria play essential roles in balancing the immune system. DF, considered nonessential nutrients in the past, is now considered to be… read more here.
Keywords: control lymphocyte; fatty acids; lymphocyte functions; short chain ... See more keywords
Essential metabolism required for T and B lymphocyte functions: an update.
Sign Up to like & getrecommendations! Published in 2023 at "Clinical science"
DOI: 10.1042/cs20220869
Abstract: Lymphocytes act as regulatory and effector cells in inflammation and infection situations. A metabolic switch towards glycolytic metabolism predominance occurs during T lymphocyte differentiation to inflammatory phenotypes (Th1 and Th17 cells). Maturation of T regulatory… read more here.
Keywords: essential metabolism; metabolism; required lymphocyte; lymphocyte functions ... See more keywords
Modulation of Lymphocyte Functions in the Microenvironment by Tumor Oncogenic Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.883639
Abstract: Despite the broad application of different immunotherapeutic strategies for the treatment of solid as well as hematopoietic cancers, the efficacy of these therapies is still limited, with only a minority of patients having a long-term… read more here.
Keywords: functions microenvironment; tumor; modulation lymphocyte; lymphocyte functions ... See more keywords
TRAF3: Guardian of T lymphocyte functions
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1129251
Abstract: Tumor necrosis factor receptor (TNFR)-associated factor 3 (TRAF3) is an adapter protein with many context-specific functions. Early studies of lymphocyte TRAF3 hinted at TRAF3’s importance for T cell function, but elucidation of specific mechanisms was… read more here.
Keywords: cell; function; guardian lymphocyte; traf3 guardian ... See more keywords