Intracellular rod-like crystals in chronic lymphocyte leukemia
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DOI: 10.1007/s12185-020-02933-7
Abstract: 1 Department of Laboratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, People’s Republic of China Fig. 1 Visible rod-like crystals presented in the mature lymphocytes (×1000, Wright Giemsa). a three rod-like… read more here.
Keywords: rod like; like crystals; rod; chronic lymphocyte ... See more keywords
STAT3 activation in large granular lymphocyte leukemia is associated with cytokine signaling and DNA hypermethylation
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DOI: 10.1038/s41375-021-01296-0
Abstract: Large granular lymphocyte leukemia (LGLL) is characterized by somatic gain-of-function STAT3 mutations. However, the functional effects of STAT3 mutations on primary LGLL cells have not been studied in detail. In this study, we show that… read more here.
Keywords: hypermethylation; granular lymphocyte; large granular; stat3 ... See more keywords
CD8‐positive cutaneous lymphoproliferation associated with large granular lymphocyte leukemia in a patient with X‐linked agammaglobulinemia
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DOI: 10.1111/cup.13860
Abstract: Patients with primary immunodeficiency are at increased risk for malignancy, especially hematologic neoplasms. This paper reports a unique case of a 47‐year‐old man with X‐linked agammaglobulinemia who presented with progressive asymptomatic violaceous papules and plaques… read more here.
Keywords: linked agammaglobulinemia; granular lymphocyte; large granular; cd8 positive ... See more keywords
Identification of a miR-146b-Fas ligand axis in the development of neutropenia in T large granular lymphocyte leukemia
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DOI: 10.3324/haematol.2019.225060
Abstract: Tlarge granular lymphocyte leukemia (T-LGLL) is characterized by the expansion of several large granular lymphocyte clones, among which a subset of large granular lymphocytes showing constitutively activated STAT3, a specific CD8+/CD4− phenotype and the presence… read more here.
Keywords: granular lymphocyte; large granular; expression; mir 146b ... See more keywords