Intra‐tumoral and peripheral blood TIGIT and PD‐1 as immune biomarkers in nodular lymphocyte predominant Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2024 at "American Journal of Hematology"
DOI: 10.1002/ajh.27459
Abstract: In classical Hodgkin lymphoma (cHL), responsiveness to immune‐checkpoint blockade (ICB) is associated with specific tumor microenvironment (TME) and peripheral blood features. The role of ICB in nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is not established.… read more here.
Keywords: peripheral blood; intra tumoral; blood; lymphocyte predominant ... See more keywords
Minimising chemotherapy while optimising immune therapy for paediatric nodular lymphocyte-predominant Hodgkin's lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Taibah University Medical Sciences"
DOI: 10.1016/j.jtumed.2020.08.004
Abstract: Nodular lymphocyte-predominant Hodgkin's lymphoma (NLPHL) is a rare but distinct subtype of Hodgkin's lymphoma (HL) that carries a better prognosis than classical Hodgkin's lymphoma. Historically, both subtypes of Hodgkin's lymphomas (classical HL and NLPHL) have… read more here.
Keywords: hodgkin lymphoma; lymphocyte predominant; hodgkin; nodular lymphocyte ... See more keywords
Rituximab in newly diagnosed stage IA nodular lymphocyte-predominant Hodgkin lymphoma: long-term follow-up of a phase 2 study from the German Hodgkin Study Group
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DOI: 10.1038/s41375-019-0609-3
Abstract: Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a distinct lymphoid malignancy accounting for ∼5% of all Hodgkin lymphoma cases. As the diseasedefining lymphocyte predominant cells consistently express CD20, CD20-directed approaches represent a treatment option in this… read more here.
Keywords: growth pattern; lymphocyte predominant; study; hodgkin ... See more keywords
Tumour cell characteristics and microenvironment composition correspond to clinical presentation in newly diagnosed nodular lymphocyte‐predominant Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Haematology"
DOI: 10.1111/bjh.18376
Abstract: Different studies have characterized the microenvironment and its prognostic impact in classic Hodgkin lymphoma whereas such analyses are pending for nodular lymphocyte‐predominant Hodgkin lymphoma (NLPHL). We thus investigated characteristics of tumour cells and microenvironment in… read more here.
Keywords: hodgkin lymphoma; hodgkin; tumour cells; lymphocyte predominant ... See more keywords
Lymphocyte-predominant lesional inflammatory infiltrates of the skin are associated with mucosal-dominant phenotype in pemphigus.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cutaneous pathology"
DOI: 10.1111/cup.14395
Abstract: INTRODUCTION Pemphigus is a potentially life-threatening autoimmune blistering disease. To date, studies assessing the association of histopathology with clinical phenotype are lacking. We sought to evaluate the main histopathologic findings and, also, the potential links… read more here.
Keywords: mucosal dominant; phenotype; lymphocyte predominant; inflammatory infiltrates ... See more keywords
Variant histology in nodular lymphocyte predominant Hodgkin lymphoma in an adult population: disease investigations and characteristics from a retrospective cohort
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pathology"
DOI: 10.1136/jclinpath-2022-208190
Abstract: A subset of variant histological patterns of nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) has been associated with advanced disease stage and increased recurrence risk. Histopathology reports on core needle (CNB) and/or surgical excision biopsies (SEB) for… read more here.
Keywords: disease; histology; lymphocyte predominant; nodular lymphocyte ... See more keywords
Abstract 6468: Nodular lymphocyte predominant hodgkin lymphoma: A national cancer database analysis with focus on hispanics
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DOI: 10.1158/1538-7445.am2024-6468
Abstract: Background:Nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) is a rare and distinct subtype of Hodgkin Lymphoma.(PMID 26149294) 80% manifest at early stages, with a male and black race predilection.(PMID 26149195) Previous analysis have shown similar survival of… read more here.
Keywords: cancer; analysis; nodular lymphocyte; lymphocyte predominant ... See more keywords
Mediastinal Nodular Lymphocyte Predominant Hodgkin Lymphoma Achieved by Endoscopic Transesophageal Cryobiopsy
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DOI: 10.1159/000518598
Abstract: Guidelines have recommended endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound-guided fine-needle aspiration biopsy as initial sampling approaches of mediastinal lymph nodes for lung cancer staging. However, the small sample volume might restrict the… read more here.
Keywords: nodular lymphocyte; cryobiopsy; predominant hodgkin; lymphocyte predominant ... See more keywords
SUMO1 modification of histone H4 is involved in the pathogenesis of nodular lymphocyte predominant Hodgkin lymphoma
Sign Up to like & getrecommendations! Published in 2020 at "Translational Cancer Research"
DOI: 10.21037/tcr-20-1994
Abstract: Background Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is a distinct and rare subtype of Hodgkin lymphoma (HL) that can be differentially diagnosed from classical Hodgkin lymphoma (cHL). Because of its low prevalence rate and undefined… read more here.
Keywords: nodular lymphocyte; predominant hodgkin; lymphoma; lymphocyte predominant ... See more keywords
Nodular lymphocyte-predominant Hodgkin lymphoma: advances in disease biology, risk stratification, and treatment
Sign Up to like & getrecommendations! Published in 2024 at "Haematologica"
DOI: 10.3324/haematol.2024.285903
Abstract: Recent updates have detailed how patients with nodular lymphocyte-predominant Hodgkin lymphoma (NLPHL) may be better risk stratified using prognostic scoring systems. Most patients with NLPHL present with early-stage disease and have an indolent disease course.… read more here.
Keywords: nodular lymphocyte; lymphocyte predominant; hodgkin lymphoma; biology ... See more keywords
Genomic Landscape of Hodgkin Lymphoma
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DOI: 10.3390/cancers13040682
Abstract: Simple Summary Hodgkin lymphoma (HL) is composed of many reactive and only a few cancer cells, so-called Hodgkin and Reed-Sternberg (HRS) or lymphocyte predominant (LP) cells. Due to the scarcity of these cells, it was… read more here.
Keywords: lymphocyte predominant; lymphoma; genomic landscape; hodgkin lymphoma ... See more keywords