Chronic lymphocytic leukemia in Brazil: A retrospective analysis of 1903 cases
Sign Up to like & getrecommendations! Published in 2017 at "American Journal of Hematology"
DOI: 10.1002/ajh.24779
Abstract: [1] Garcia-Manero G. Myelodysplastic syndromes: 2015 Update on diagnosis, risk-stratification and management. Am J Hematol. 2015;90: 831–841. [2] Arber DA, Orazi A, Hasserjian R, et al. The 2016 revision to the World Health Organization classification… read more here.
Keywords: myelodysplastic syndromes; brazil retrospective; lymphocytic leukemia; leukemia brazil ... See more keywords
A pilot study of the effect of atorvastatin on endothelial function and albuminuria in sickle cell disease
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25614
Abstract: 1. Henter JI, Horne A, Arico M, et al. HLH-2004: diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis. Pediatr Blood Cancer. 2007;48(2):124-131. 2. U.S. Food and Drug Administration. Center for Drug Evaluation and Research. Imbruvica NDA… read more here.
Keywords: lymphocytic leukemia; lymphohistiocytosis; hemophagocytic lymphohistiocytosis; chronic lymphocytic ... See more keywords
Increasing prevalence of chronic lymphocytic leukemia with an estimated future rise: A nationwide population‐based study
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Hematology"
DOI: 10.1002/ajh.25681
Abstract: Increasing prevalence of chronic lymphocytic leukemia with an estimated future rise : a nationwide population-based study read more here.
Keywords: leukemia estimated; lymphocytic leukemia; estimated future; prevalence chronic ... See more keywords
Prediction of outcomes in chronic lymphocytic leukemia patients treated with ibrutinib: Validation of current prognostic models and development of a simplified three‐factor model
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26502
Abstract: apixaban with major ischemic or hemorrhagic events in patients with atrial fibrillation. JAMA. 2021;326(23):2395-2404. 3. Ortel TL, Neumann I, Ageno W, et al. American Society of Hematology 2020 guidelines for management of venous thromboembolism: treatment… read more here.
Keywords: hematology; chronic lymphocytic; outcomes chronic; lymphocytic leukemia ... See more keywords
Management of front line chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26677
Abstract: Treatment options with targeted agents have changed the treatment landscape of CLL profoundly. Besides chemoimmunotherapy, treatment regimen approved for frontline therapy include continuous treatment with BTK inhibitors like ibrutinib and acalabrutinib or fixed‐duration regimen like… read more here.
Keywords: front line; lymphocytic leukemia; chronic lymphocytic; management front ... See more keywords
Orelabrutinib in relapsed or refractory chronic lymphocytic leukemia/small lymphocytic lymphoma patients: Multi‐center, single‐arm, open‐label, phase 2 study
Sign Up to like & getrecommendations! Published in 2023 at "American Journal of Hematology"
DOI: 10.1002/ajh.26826
Abstract: Orelabrutinib is a novel, small molecule, selective irreversible Bruton's tyrosine kinase inhibitor. The aim of this study was to evaluate the efficacy and safety in patients with refractory or relapsed chronic lymphocytic leukemia (CLL)/small lymphocytic… read more here.
Keywords: lymphocytic leukemia; orelabrutinib; small lymphocytic; chronic lymphocytic ... See more keywords
Efficacy of bendamustine and rituximab in unfit patients with previously untreated chronic lymphocytic leukemia. Indirect comparison with ibrutinib in a real‐world setting. A GIMEMA‐ERIC and US study
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3470
Abstract: Limited information is available on the efficacy of front‐line bendamustine and rituximab (BR) in chronic lymphocytic leukemia (CLL) with reduced renal function or coexisting conditions. We therefore analyzed a cohort of real‐world patients and performed… read more here.
Keywords: real world; ibrutinib; lymphocytic leukemia; bendamustine rituximab ... See more keywords
Secondary malignancies and survival of FCR‐treated patients with chronic lymphocytic leukemia in Central Europe
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5033
Abstract: This is the first large‐scale cross‐country analysis of patients with chronic lymphocytic leukemia (CLL) aimed to evaluate the incidence, types, and key prognostic factors of secondary malignancies, and to assess the impact on overall survival… read more here.
Keywords: patients chronic; lymphocytic leukemia; secondary malignancies; treated patients ... See more keywords
A comprehensive assessment of lymphocyte subsets, their prognostic significance, and changes after first‐line therapy administration in patients with chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.5492
Abstract: In chronic lymphocytic leukemia (CLL), changes in the peripheral blood lymphocyte subsets play an important role in disease progression and infectious complications. The impact of chemoimmunotherapy (CIT) on these changes has not been extensively studied read more here.
Keywords: chronic lymphocytic; lymphocyte subsets; comprehensive assessment; lymphocytic leukemia ... See more keywords
Comorbidities predict inferior outcomes in chronic lymphocytic leukemia treated with ibrutinib
Sign Up to like & getrecommendations! Published in 2018 at "Cancer"
DOI: 10.1002/cncr.31554
Abstract: Most patients with chronic lymphocytic leukemia (CLL) present with multiple comorbidities. Although comorbidities negatively affect outcomes for patients treated with chemoimmunotherapy, their impact on patients who receive targeted therapies is unknown. read more here.
Keywords: lymphocytic leukemia; inferior outcomes; comorbidities predict; predict inferior ... See more keywords
Novel combination approaches with targeted agents in frontline chronic lymphocytic leukemia
Sign Up to like & getrecommendations! Published in 2022 at "Cancer"
DOI: 10.1002/cncr.34510
Abstract: Targeted therapies have revolutionized the frontline treatment landscape for patients with chronic lymphocytic leukemia (CLL) and have largely displaced a reliance on chemoimmunotherapy when treating this disease. Multiple randomized trials have documented the efficacy of… read more here.
Keywords: chronic lymphocytic; treatment landscape; combination; lymphocytic leukemia ... See more keywords