Hypofibrinogenemia Is Associated With Poor Outcome and Secondary Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome in Pediatric Severe Sepsis*
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DOI: 10.1097/pcc.0000000000001507
Abstract: Objectives: Some children with sepsis exhibit a sustained hyperinflammatory response that can trigger secondary hemophagocytic lymphohistiocytosis/macrophage activation syndrome. Although hypofibrinogenemia is a shared feature of sepsis and hemophagocytic lymphohistiocytosis, there are no data about fibrinogen… read more here.
Keywords: macrophage activation; lymphohistiocytosis; activation syndrome; hemophagocytic lymphohistiocytosis ... See more keywords