Comparative Study of Ectopic Lymphoid Aggregates in Sheep and Murine Models of Bleomycin-Induced Pulmonary Fibrosis
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DOI: 10.1155/2023/1522593
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic disease characterized by excessive deposition of extracellular matrix in the interstitial lung parenchyma, often manifested by dyspnea and progressive loss of lung function. The role of inflammation in… read more here.
Keywords: lymphoid aggregates; lung; pulmonary fibrosis; lung tissues ... See more keywords
IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD
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DOI: 10.1186/s12931-017-0641-7
Abstract: BackgroundIncreased interferon gamma (IFNγ) release occurs in Chronic Obstructive Pulmonary Disease (COPD) lungs. IFNγ supports optimal viral clearance, but if dysregulated could increase lung tissue destruction.MethodsThe present study investigates which mediators most closely correlate with… read more here.
Keywords: lymphoid aggregates; production; disease; copd ... See more keywords
Lymphoid aggregates in the bone marrow biopsies of patients with myelodysplastic syndromes – A potential prognostic marker?
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DOI: 10.3389/fonc.2022.988998
Abstract: Background Lymphoid aggregates (LA) are occasionally seen in bone marrow biopsies (BMB) of myelodysplastic syndromes (MDS) patients. Our aim was to evaluate their incidence and association with prognosis. Methods We compared BMB reports of MDS… read more here.
Keywords: mds; marrow biopsies; lymphoid aggregates; bone marrow ... See more keywords