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   Articles with "lymphoid neoplasms" as a keyword



Altered Spectrum of Lymphoid Neoplasms in a Single-Center Cohort of Common Variable Immunodeficiency with Immune Dysregulation

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recommendations! Published in 2021 at "Journal of Clinical Immunology"

DOI: 10.1007/s10875-021-01016-4

Abstract: Purpose Common variable immune deficiency (CVID) confers an increased risk of lymphoid neoplasms, but reports describing the precise WHO specification of the lymphoma subtypes and their immunological environment are lacking. We therefore classified lymphomas—occurring in… read more here.

Keywords: lymphoma; lymphoid neoplasms; common variable; cohort ... See more keywords
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Diagnostically relevant updates to the 2017 WHO classification of lymphoid neoplasms.

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recommendations! Published in 2018 at "Annals of diagnostic pathology"

DOI: 10.1016/j.anndiagpath.2018.09.011

Abstract: The recent 2017 WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues contains a number of updates under the category of lymphoid neoplasms. These changes include introduction of new entities, amended classification or terminology, and… read more here.

Keywords: classification; relevant updates; updates 2017; diagnostically relevant ... See more keywords
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Myeloid/lymphoid neoplasms with eosinophilia and FLT3 rearrangement.

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recommendations! Published in 2020 at "Leukemia research"

DOI: 10.1016/j.leukres.2020.106460

Abstract: Myeloid/lymphoid neoplasms with eosinophilia and gene rearrangement are a unique category in the WHO classification, and include cases with rearrangement of PDGFRA, PDGFRB, FGFR1, and PCM1-JAK2. We report three patients presented with eosinophilia and FLT3… read more here.

Keywords: flt3 rearrangement; lymphoid neoplasms; neoplasms eosinophilia; myeloid lymphoid ... See more keywords
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Targeted massively parallel sequencing of mature lymphoid neoplasms: assessment of empirical application and diagnostic utility in routine clinical practice

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recommendations! Published in 2020 at "Modern Pathology"

DOI: 10.1038/s41379-020-00720-7

Abstract: Massively parallel sequencing (MPS) has become a viable diagnostic tool to interrogate genetic profiles of numerous tumors but has yet to be routinely adopted in the setting of lymphoma. Here, we report the empirical application… read more here.

Keywords: massively parallel; empirical application; lymphoid neoplasms; application ... See more keywords

Maintenance 5-azacytidine therapy by MRD monitoring after allogeneic HSCT in myeloid/lymphoid neoplasms with FGFR1 rearrangement

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recommendations! Published in 2019 at "Bone Marrow Transplantation"

DOI: 10.1038/s41409-019-0436-1

Abstract: Myeloid/lymphoid neoplasms with fibroblast growth factor receptor 1 (FGFR1) rearrangement are rare hematological malignancies. In the 2016 World Health Organization classification, they are listed in myeloid/lymphoid neoplasms associated with eosinophilia and rearrangement of PDGFRA, PDGFRB,… read more here.

Keywords: fgfr1 rearrangement; lymphoid neoplasms; neoplasms fgfr1; fgfr1 ... See more keywords

Pemigatinib for the treatment of myeloid/lymphoid neoplasms with FGFR1 rearrangement

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recommendations! Published in 2023 at "Expert Review of Anticancer Therapy"

DOI: 10.1080/14737140.2023.2192930

Abstract: ABSTRACT Introduction Myeloid/lymphoid neoplasms with fibroblast growth factor receptor-1 (FGFR1) rearrangements (MLNFGFR1) are rare entities with aggressive features and poor prognosis. Presentation is heterogeneous, ranging from myeloproliferative neoplasms (with or without eosinophilia) to T-cell lymphoma… read more here.

Keywords: lymphoid neoplasms; fgfr1; pemigatinib; treatment ... See more keywords

Complete response of myeloid/lymphoid neoplasms with PDGFRA rearrangement presenting as leukemia/myeloid sarcoma to imatinib monotherapy

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recommendations! Published in 2019 at "Chinese Medical Journal"

DOI: 10.1097/cm9.0000000000000437

Abstract: of myeloperoxidase, CD34, and CD117. Blood tests To the Editor: The presence of FIP-1-like-1-platelet-derived growth factor receptor-a (FIP1L1-PDGFRA, F/P) fusion identified the presence of eosinophilia (3.86 10/L, 49.2% gene accounts for approximately 23% (3%–56%) of… read more here.

Keywords: myeloid; pdgfra; pdgfra rearrangement; myeloid lymphoid ... See more keywords

The Use of Optical Genome Mapping for the Detection of Tyrosine Kinase Gene Fusions in Myeloid/Lymphoid Neoplasms

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recommendations! Published in 2025 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.70640

Abstract: Myeloid/Lymphoid Neoplasms with eosinophilia and involvement of Tyrosine Kinase gene fusions (MLN‐TK) is a WHO disease category including a diverse group of malignancies characterised by recurrent genomic rearrangements of tyrosine kinase (TK) genes such as… read more here.

Keywords: lymphoid neoplasms; tyrosine kinase; myeloid lymphoid; kinase gene ... See more keywords

Identification and Confirmation of Myeloid/Lymphoid Neoplasms With Fibroblast Growth Factor Receptor 1 Rearrangement and Characterization of Treatment Patterns and Outcomes in a Real-World Setting: A US Retrospective Chart Review.

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recommendations! Published in 2025 at "Acta haematologica"

DOI: 10.1159/000546910

Abstract: INTRODUCTION Myeloid/lymphoid neoplasms with fibroblast growth factor receptor 1 rearrangement (MLN-FGFR1) are rare, heterogenous, aggressive hematologic malignancies with FGFR1 rearrangements at the 8p11 locus. Pemigatinib, a potent selective inhibitor of FGFR1-3, is approved for relapsed/refractory… read more here.

Keywords: lymphoid neoplasms; fibroblast growth; mln fgfr1; neoplasms fibroblast ... See more keywords

The International Consensus Classification of Mature Lymphoid Neoplasms: A Report from the Clinical Advisory Committee.

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recommendations! Published in 2022 at "Blood"

DOI: 10.1182/blood.2022015851

Abstract: Since the publication of the Revised European-American Classification of mature lymphoid neoplasms in 1994, subsequent updates of the classification of mature lymphoid neoplasms have been generated through iterative international efforts to achieve broad consensus among… read more here.

Keywords: consensus; lymphoid neoplasms; classification; mature lymphoid ... See more keywords

Genomic Profiling for Clinical Decision Making in Lymphoid Neoplasms.

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recommendations! Published in 2022 at "Blood"

DOI: 10.1182/blood.2022015854

Abstract: With the introduction of large-scale molecular profiling methods and high-throughput sequencing technologies, the genomic features of most lymphoid neoplasms have been characterized at an unprecedented scale. While the principles for the classification and diagnosis of… read more here.

Keywords: profiling clinical; genomic profiling; clinical decision; lymphoid neoplasms ... See more keywords