Quantitative differentiation of whole smoke solution‐induced mutagenicity in the mouse lymphoma assay
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DOI: 10.1002/em.22151
Abstract: In vitro genotoxicity dose–response data have been investigated for their utility in modeling and assessing potential differences in mutagenic responses between machine‐generated whole smoke solutions (WSSs) from combusted cigarette tobacco products. Our previous study observed… read more here.
Keywords: whole smoke; potency; mouse lymphoma; lymphoma assay ... See more keywords
Evaluation of U. S. National Toxicology Program (NTP) mouse lymphoma assay data using International Workshop on Genotoxicity Tests (IWGT) and the Organization for Economic Co‐Operation and Development (OECD) criteria
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DOI: 10.1002/em.22250
Abstract: The forward gene mutation mouse lymphoma assay (MLA) is widely used, as part of a regulatory test battery, to identify the genotoxic potential of chemicals. It identifies mutagens capable of inducing a variety of genetic… read more here.
Keywords: program ntp; mouse lymphoma; toxicology program; lymphoma assay ... See more keywords