Cytotoxic and apoptotic activity of nitrofuroxans on lymphoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Chemistry of Heterocyclic Compounds"
DOI: 10.1007/s10593-018-2232-z
Abstract: Five nitrofuroxans were synthesized and evaluated for their in vitro cytotoxicity against human lymphoma cells with different p53 status (Raji Burkitt's lymphoma and MOLT-4). The most promising compound exhibited IC50 values of 2.6–11.0 μM in… read more here.
Keywords: activity nitrofuroxans; microscopy; lymphoma cells; nitrofuroxans lymphoma ... See more keywords
Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Oncology"
DOI: 10.1007/s13402-018-0397-1
Abstract: PurposePreviously, compounds containing a piperidone structure have been shown to be highly cytotoxic to cancer cells. Recently, we found that the piperidone compound P2 exhibits a potent anti-neoplastic activity against human breast cancer-derived cells. Here,… read more here.
Keywords: lymphoma cells; induction; leukemia lymphoma; piperidone ... See more keywords
Differential role of FL-BID and t-BID during verotoxin-1-induced apoptosis in Burkitt’s lymphoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Oncogene"
DOI: 10.1038/s41388-018-0123-5
Abstract: The globotriaosylceramide Gb3 is a glycosphingolipid expressed on a subpopulation of germinal center B lymphocytes which has been recognized as the B cell differentiation antigen CD77. Among tumoral cell types, Gb3/CD77 is strongly expressed in… read more here.
Keywords: lymphoma cells; bid bid; bid; burkitt lymphoma ... See more keywords
The reciprocal interplay between TNFα and the circadian clock impacts on cell proliferation and migration in Hodgkin lymphoma cells
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-29847-z
Abstract: A bidirectional interaction between the circadian network and effector mechanisms of immunity brings on a proper working of both systems. In the present study, we used Hodgkin lymphoma (HL) as an experimental model for a… read more here.
Keywords: lymphoma; tnf; hodgkin lymphoma; lymphoma cells ... See more keywords
Immunohistochemical and Immunocytochemical Analyses in Patients with Vitreoretinal Lymphoma
Sign Up to like & getrecommendations! Published in 2018 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2018.1533984
Abstract: ABSTRACT Purpose: The aim of this study was to analyze immunohistochemical and immunocytological findings by examining enucleated eyes and vitreous cell block (CB) in patients with vitreoretinal lymphoma (VRL). Methods: Histological specimens were obtained from… read more here.
Keywords: enucleated eyes; immunocytochemical analyses; lymphoma cells; immunohistochemical immunocytochemical ... See more keywords
Novel prognostic predictor of haemoglobin-platelet index in diffuse large B-cell lymphoma, not otherwise specified: Anaemia and thrombocytopenia are associated with IL-6 production in lymphoma cells.
Sign Up to like & getrecommendations! Published in 2022 at "British journal of haematology"
DOI: 10.1111/bjh.18208
Abstract: We previously reported that a novel haemoglobin-platelet index (HPI) based on anaemia and thrombocytopenia was useful to predict the prognosis of patients with diffuse large B-cell lymphoma not otherwise specified (DLBCL NOS). Here, we analyse… read more here.
Keywords: platelet index; lymphoma cells; lymphoma; anaemia thrombocytopenia ... See more keywords
Pyruvate secreted from patient‐derived cancer‐associated fibroblasts supports survival of primary lymphoma cells
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Science"
DOI: 10.1111/cas.13873
Abstract: Cancer‐associated fibroblasts (CAF) are a key component in the tumor microenvironment and play functional roles in tumor metastasis and resistance to chemotherapies. We have previously reported that CAF isolated from lymphoma samples increase anaerobic glycolysis… read more here.
Keywords: lymphoma; lymphoma cells; associated fibroblasts; cancer associated ... See more keywords
Differentiation of Hodgkin lymphoma cells by reactive oxygen species and regulation by heme oxygenase‐1 through HIF‐1α
Sign Up to like & getrecommendations! Published in 2021 at "Cancer Science"
DOI: 10.1111/cas.14890
Abstract: We previously indicated that Hodgkin lymphoma (HL) cells contain a small side population (SP) that differentiate into a large major population (MP) with giant Hodgkin and Reed‐Sternberg (H and RS)‐like cells. However, its molecular mechanisms… read more here.
Keywords: reactive oxygen; hif; hodgkin lymphoma; oxygen species ... See more keywords
A System Based on Novel Parainfluenza Virus PIV5-L for Efficient Gene Delivery of B-Lymphoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Virology"
DOI: 10.1128/jvi.00257-22
Abstract: B-cell lymphoma is a common aggressive neoplastic disorder of lymphocytes. Delivery of genes of interest into B cells, particularly virus-mediated B-lymphoma cells, is still a challenge. In this study, we report that a system (L-VLP)… read more here.
Keywords: lymphoma cells; gene; virus; cell ... See more keywords
BCR Loss Reduces the Fitness of MYC-Driven Lymphoma Cells.
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DOI: 10.1158/2159-8290.cd-rw2017-109
Abstract: BCR-proficient lymphoma cells exhibit a competitive growth advantage in vitro and in vivo. read more here.
Keywords: fitness myc; lymphoma cells; bcr loss; loss reduces ... See more keywords
Lymphoma Cells Are Retained in Gliotic Nervous-System Tissue.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2019-146
Abstract: Lymphoma cells were more likely to take hold in gliotic central nervous systems (CNS) in mice. read more here.
Keywords: gliotic nervous; retained gliotic; lymphoma cells; nervous system ... See more keywords