Genetic characterization of MYD88-mutated lymphoplasmacytic lymphoma in comparison with MYD88-mutated chronic lymphocytic leukemia
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DOI: 10.1038/leu.2016.330
Abstract: MYD88 (myeloid differentiation primary response 88) is mutated in the majority of Waldenström macroglobulinemia/lymphoplasmacytic lymphoma (LPL); but also, albeit less frequently, in other B-cell malignancies, including chronic lymphocytic leukemia (CLL). This suggests MYD88 as a… read more here.
Keywords: cll; lymphocytic leukemia; lymphoplasmacytic lymphoma; chronic lymphocytic ... See more keywords
Acute kidney injury due to direct infiltration by lymphoplasmacytic lymphoma secreting IgG paraproteins
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DOI: 10.1097/md.0000000000029449
Abstract: Abstract Introduction: Waldenström's macroglobulinemia is a lymphoplasmacytic lymphoma (LPL) associated with a monoclonal immunoglobulin M protein. Although acute kidney injury (AKI) due to immunoglobulin M paraprotein infiltration into the renal interstitium has been reported, there… read more here.
Keywords: acute kidney; kidney injury; immunoglobulin; lymphoplasmacytic lymphoma ... See more keywords
Clinical characteristic and outcome of lymphoplasmacytic lymphoma of non‐Waldenstrom macroglobulinemia type: A Swedish lymphoma registry study
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DOI: 10.1111/bjh.18002
Abstract: Lymphoplasmacytic lymphoma (LPL) not fulfilling the WHO diagnostic criteria (2017) for Waldenstrom’s macroglobulinemia (WM) (named non‐WM LPL) is a rare disease and only a few systematic studies have been published. Here, we present a population‐based… read more here.
Keywords: waldenstrom macroglobulinemia; lymphoma; diagnosis; lymphoplasmacytic lymphoma ... See more keywords
Preneoplastic somatic mutations including MYD88L265P in lymphoplasmacytic lymphoma
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DOI: 10.1126/sciadv.abl4644
Abstract: Normal cell counterparts of solid and myeloid tumors accumulate mutations years before disease onset; whether this occurs in B lymphocytes before lymphoma remains uncertain. We sequenced multiple stages of the B lineage in elderly individuals… read more here.
Keywords: lymphoma; lymphoplasmacytic lymphoma; including myd88l265p; preneoplastic somatic ... See more keywords
Lymphoplasmacytic Lymphoma Presenting with Diarrhea and Joint Pain Which was Successfully Diagnosed by an MYD88 Mutation Analysis
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DOI: 10.2169/internalmedicine.56.7340
Abstract: A 55-year-old man presented to our department with diarrhea, weight loss, fatigability, and polyarthralgia. Blood tests revealed elevated soluble interleukin-2 receptor levels and IgG-type M protein positivity, without any findings that were suggestive of collagen… read more here.
Keywords: lymphoma; lymphoma presenting; lymphoplasmacytic lymphoma; mutation analysis ... See more keywords
Survival of patients with lymphoplasmacytic lymphoma and solitary plasmacytoma in Germany and the United States of America in the early 21st century
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DOI: 10.3324/haematol.2016.157768
Abstract: Population-level survival has increased for a number of hematologic malignancies.[1][1]–[3][2] Multiple myeloma, in particular, has seen improved survival both in clinical trials[4][3]–[8][4] and on the population level.[3][2],[9][5]–[11][6] However, it is not known whether the changes… read more here.
Keywords: patients lymphoplasmacytic; lymphoplasmacytic lymphoma; lymphoma solitary; survival patients ... See more keywords
Determinants of Drug Resistance in B-Cell Non-Hodgkin Lymphomas: The Case of Lymphoplasmacytic Lymphoma/Waldenström Macroglobulinemia
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DOI: 10.3389/fonc.2021.801124
Abstract: Lymphoplasmacytic lymphoma (LPL) is a rare subtype of B cell-derived non-Hodgkin lymphoma characterized by the abnormal growth of transformed clonal lymphoplasmacytes and plasma cells. This tumor almost always displays the capability of secreting large amounts… read more here.
Keywords: non hodgkin; lymphoma; lymphoplasmacytic lymphoma; waldenstr macroglobulinemia ... See more keywords