Lymphopenia-induced lymphoproliferation drives activation of naive T cells and expansion of regulatory populations
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DOI: 10.1016/j.isci.2021.102164
Abstract: Summary Chemotherapy pre-conditioning is an essential component of chimeric antigen receptor transduced cell therapy. Acute lymphopenia-induced proliferation (LIP) is known to be driven primarily by homeostatic cytokines, but little is known on the underlying mechanisms… read more here.
Keywords: expansion; lymphoproliferation drives; induced lymphoproliferation; lymphopenia induced ... See more keywords