Salivary factor LTRIN from Aedes aegypti facilitates the transmission of Zika virus by interfering with the lymphotoxin-β receptor
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0063-9
Abstract: Pathogens have co-evolved with mosquitoes to optimize transmission to hosts. Mosquito salivary-gland extract is known to modulate host immune responses and facilitate pathogen transmission, but the underlying molecular mechanisms of this have remained unknown. In… read more here.
Keywords: aedes aegypti; lymphotoxin receptor; ltrin; transmission zika ... See more keywords
Pathological significance and regulatory mechanism of lymphotoxin β receptor overexpression in T cells of patients with systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biomedical Research"
DOI: 10.7555/jbr.27.20130046
Abstract: Systemic lupus erythematosus (SLE) is a typical autoimmune disease. Lymphotoxin β receptor (LTβR) signaling plays an important role in autoimmune inflammations. LTβR-Ig fusion protein, LTβR blocking agent, has been used to treat SLE, while its… read more here.
Keywords: systemic lupus; cells sle; lymphotoxin receptor; lupus erythematosus ... See more keywords