Dietary l-lysine supplementation altered the content of pancreatic polypeptide, enzymes involved in glutamine metabolism, and β-actin in rats
Sign Up to like & getrecommendations! Published in 2018 at "Amino Acids"
DOI: 10.1007/s00726-018-2648-x
Abstract: This study investigated the effects of Lys supplementation on serum pancreatic polypeptide (PP), glutamine (Gln) levels and the expression of PP, Gln synthetase (GlnS), glutaminase (Gls) and β-actin in different tissues such as pancreas, skeletal… read more here.
Keywords: supplementation; actin; muscle; lys ... See more keywords
Lipopolysaccharide-Elicited Systemic Inflammation Induces Selective Vulnerability of Cerebral Cortex and Striatum of Developing Glutaryl-CoA Dehydrogenase Deficient (Gcdh-/-) Mice to Oxidative Stress.
Sign Up to like & getrecommendations! Published in 2020 at "Neurotoxicity research"
DOI: 10.1007/s12640-020-00291-0
Abstract: We investigated redox homeostasis in cerebral and peripheral tissues of wild type (WT) and glutaryl-CoA dehydrogenase knockout mice (Gcdh-/-) submitted to inflammation induced by lipopolysaccharide (LPS) since patients with glutaric aciduria type I (GA I)… read more here.
Keywords: cerebral cortex; lys; mice; gcdh mice ... See more keywords
Determination of the optimum standardised ileal digestible sulphur amino acids to lysine ratio in weaned pigs challenged with enterotoxigenic Escherichia coli
Sign Up to like & getrecommendations! Published in 2017 at "Animal Feed Science and Technology"
DOI: 10.1016/j.anifeedsci.2017.03.004
Abstract: This experiment tested the hypothesis that pigs challenged with an enterotoxigenic strain of E. coli (ETEC) would require a higher sulphur amino acids (SAA) to Lys ratio (SAA:Lys). Pigs (n = 120) weighing 7.4 ±… read more here.
Keywords: standardised ileal; saa lys; lys; sid saa ... See more keywords
Electrostatic-driven structural transformation in the complexation of lysozyme and κ-carrageenan
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Physics"
DOI: 10.1016/j.chemphys.2020.110910
Abstract: Abstract Lysozyme (LYS) and κ-carrageenan (κ-CRG) are important components widely used in food and pharmaceutical products. In this work, we investigated the interactions in the aqueous mixtures of LYS and κ-CRG and the structural transformation… read more here.
Keywords: lys crg; structural transformation; lys; lysozyme ... See more keywords
Genipin cross-linked blue Lys-FA nanoparticles for targeted visible glioma cell staining and drug delivery
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.102161
Abstract: Abstract Design and fabrication of multifunctional nano-carrier is a promising tool in the field of nanomedicine for glioma theranostics. In this study, blue color nanoparticles with targeted tumor cell staining and drug delivery capabilities were… read more here.
Keywords: lys nps; drug delivery; lys; spectroscopy ... See more keywords
Evaluation of toxicity of functionalized graphene oxide with ginsenoside Rh2, lysine and arginine on blood cancer cells (K562), red blood cells, blood coagulation and cardiovascular tissue: In vitro and in vivo studies
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Taiwan Institute of Chemical Engineers"
DOI: 10.1016/j.jtice.2018.08.010
Abstract: Abstract In this study, blood- and cardio-toxicity of Rh2–treated graphene oxide (GO-Rh2), lysine-treated graphene oxide (GO-Lys), arginine-treated GO (GO-Arg), Rh2–treated GO-Lys (GO-Lys-Rh2) and Rh2–treated GO-Arg (GO-Arg-Rh2) were evaluated. Two concentrations of each nanostructures (200 and… read more here.
Keywords: rh2; lys; tissue; toxicity ... See more keywords
Effects of reducing dietary content of crude protein and indispensable amino acids on performance and carcass traits of single-phase- and 2-phase-fed growing-finishing pigs
Sign Up to like & getrecommendations! Published in 2019 at "Livestock Science"
DOI: 10.1016/j.livsci.2019.04.014
Abstract: Abstract Effects of reducing dietary content of crude protein (CP) and Lys on performance and carcass traits of growing-finishing pigs were studied in 690 crossbred (Swedish Yorkshire dams x Hampshire sires) female and vaccinated entire… read more here.
Keywords: lys; phase phase; phase fed; fed pigs ... See more keywords
Studies of ternary complexes formed in the biocoordination systems including copper(II) ions, polyamines and l-lysine
Sign Up to like & getrecommendations! Published in 2019 at "Polyhedron"
DOI: 10.1016/j.poly.2019.114137
Abstract: Abstract Complexation reactions of Cu(II) in the system with l -lysine as well as biogenic amines – PA (putrescine – Put, spermidine – Spd and spermine – Spm) were investigated. It was found that at… read more here.
Keywords: formed biocoordination; complexes formed; ternary complexes; studies ternary ... See more keywords
Design and rationale of the LYS-SAF302 gene therapy study in mucopolysaccharidosis type IIIA (MPS IIIA) children
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Genetics and Metabolism"
DOI: 10.1016/j.ymgme.2018.12.283
Abstract: Mucopolysaccharidosis type IIIA (MPS IIIA) (OMIM 252900) leads to early-onset neurodegeneration and premature death. Though the involvement of multiple organ systems in MPS IIIA is recognized, central nervous system (CNS) manifestations predominate, in particular intellectual… read more here.
Keywords: lys; mps iiia; study; gene therapy ... See more keywords
Nonpyrogenic Molecular Adjuvants Based on norAbu-Muramyldipeptide and norAbu-Glucosaminyl Muramyldipeptide: Synthesis, Molecular Mechanisms of Action, and Biological Activities in Vitro and in Vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00593
Abstract: Fatty acyl analogues of muramyldipeptide (MDP) (abbreviated N-L18 norAbuGMDP, N-B30 norAbuGMDP, norAbuMDP-Lys(L18), norAbuMDP-Lys(B30), norAbuGMDP-Lys(L18), norAbuGMDP-Lys(B30), B30 norAbuMDP, L18 norAbuMDP) are designed and synthesized comprising the normuramyl-l-α-aminobutanoyl (norAbu) structural moiety. All new analogues show depressed pyrogenicity… read more here.
Keywords: lys b30; norabumdp lys; lys; b30 ... See more keywords
Malondialdehyde-Induced Post-translational Modifications in Hemoglobin of Smokers by NanoLC-NSI/MS/MS Analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00442
Abstract: Malondialdehyde (MDA) is the most abundant α,β-unsaturated aldehyde generated from endogenous peroxidation of polyunsaturated fatty acids and is present in cigarette smoke. Post-translational modifications of blood hemoglobin can serve as biomarkers for exposure to chemicals.… read more here.
Keywords: translational modifications; post translational; modifications hemoglobin; lys lys ... See more keywords