Characterization of a Potent and Orally Bioavailable Lys-Covalent Inhibitor of Apoptosis Protein (IAP) Antagonist.
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DOI: 10.1021/acs.jmedchem.3c00467
Abstract: We have recently reported on the use of aryl-fluorosulfates in designing water- and plasma-stable agents that covalently target Lys, Tyr, or His residues in the BIR3 domain of the inhibitor of the apoptosis protein (IAP)… read more here.
Keywords: inhibitor apoptosis; lys covalent; protein iap; apoptosis protein ... See more keywords