SDS-induced oligomerization of Lys49-phospholipase A2 from snake venom
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DOI: 10.1038/s41598-019-38861-8
Abstract: Phospholipase A2 (PLA2) is one of the representative toxic components of snake venom. PLA2s are categorized into several subgroups according to the amino acid at position 49, which comprises either Asp49, Lys49, Arg49 or Ser49.… read more here.
Keywords: lys49 pla2; phospholipase; lys49; sds ... See more keywords
Inflammasome Activation Induced by a Snake Venom Lys49-Phospholipase A2 Homologue
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DOI: 10.3390/toxins12010022
Abstract: Background: Snake venom phospholipases A2 (PLA2s) have hemolytic, anticoagulant, myotoxic, oedematogenic, bactericidal, and inflammatory actions. BthTX-I, a Lys49-PLA2 isolated from Bothrops jararacussu venom, is an example of Lys49-PLA2 that presents such actions. NLRP3 is a… read more here.
Keywords: inflammasome activation; activation induced; induced snake; activation ... See more keywords