Articles with "lys49 pla2" as a keyword



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SDS-induced oligomerization of Lys49-phospholipase A2 from snake venom

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Published in 2019 at "Scientific Reports"

DOI: 10.1038/s41598-019-38861-8

Abstract: Phospholipase A2 (PLA2) is one of the representative toxic components of snake venom. PLA2s are categorized into several subgroups according to the amino acid at position 49, which comprises either Asp49, Lys49, Arg49 or Ser49.… read more here.

Keywords: lys49 pla2; phospholipase; lys49; sds ... See more keywords

Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus

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Published in 2021 at "Scientific Reports"

DOI: 10.1038/s41598-021-98594-5

Abstract: Viperid snake venoms contain a unique family of cytotoxic proteins, the Lys49 PLA2 homologs, which are devoid of enzymatic activity but disrupt the integrity of cell membranes. They are known to induce skeletal muscle damage… read more here.

Keywords: lys49 pla2; myotoxin; rat cardiomyocytes; snake venom ... See more keywords