A LysargiNase- and chemical derivatization-based strategy LAACTer facilitating in-depth profiling of C-terminome.
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DOI: 10.1021/acs.analchem.9b03543
Abstract: Global identification of protein C-termini is highly challenging due to their low abundance in conventional shotgun proteomics. Several enrichment strategies has been developed to facilitate the detection of C-terminal peptides. One major issue of previous… read more here.
Keywords: depth; lysarginase chemical; terminome; chemical ... See more keywords