Return of the lysergamides. Part V: Analytical and behavioural characterization of 1-butanoyl-d-lysergic acid diethylamide (1B-LSD).
Sign Up to like & getrecommendations! Published in 2019 at "Drug testing and analysis"
DOI: 10.1002/dta.2613
Abstract: The psychedelic properties of lysergic acid diethylamide (LSD) have captured the imagination of researchers for many years and its rediscovery as an important research tool is evidenced by its clinical use within neuroscientific and therapeutic… read more here.
Keywords: lsd; spectroscopy; diethylamide lsd; lysergic acid ... See more keywords
In vitro metabolic fate of nine LSD-based new psychoactive substances and their analytical detectability in different urinary screening procedures
Sign Up to like & getrecommendations! Published in 2019 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1558-9
Abstract: The market of new psychoactive substances (NPS) is characterized by a high turnover and thus provides several challenges for analytical toxicology. The analysis of urine samples often requires detailed knowledge about metabolism given that parent… read more here.
Keywords: psychoactive substances; screening; lsd; lsd lsd ... See more keywords
Dark Classics in Chemical Neuroscience: Lysergic Acid Diethylamide (LSD).
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00043
Abstract: Lysergic acid diethylamide (LSD) is one of the most potent psychoactive agents known, producing dramatic alterations of consciousness after submilligram (≥20 μg) oral doses. Following the accidental discovery of its potent psychoactive effects in 1943,… read more here.
Keywords: diethylamide lsd; chemical neuroscience; lsd; acid diethylamide ... See more keywords
Metabolism of lysergic acid diethylamide (LSD): an update
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DOI: 10.1080/03602532.2019.1638931
Abstract: Abstract Lysergic acid diethylamide (LSD) is the most potent hallucinogen known and its pharmacological effect results from stimulation of central serotonin receptors (5-HT2). Since LSD is seen as physiologically safe compound with low toxicity, its… read more here.
Keywords: diethylamide lsd; metabolism; lsd; acid diethylamide ... See more keywords
Lysergic acid diethylamide causes photoreceptor cell damage through inducing inflammatory response and oxidative stress
Sign Up to like & getrecommendations! Published in 2018 at "Cutaneous and Ocular Toxicology"
DOI: 10.1080/15569527.2018.1423620
Abstract: Abstract Lysergic acid diethylamide (LSD), a classical hallucinogen, was used as a popular and notorious substance of abuse in various parts of the world. Its abuse could result in long-lasting abnormalities in retina and little… read more here.
Keywords: photoreceptor cell; photoreceptor; acid diethylamide; lysergic acid ... See more keywords
Quantitative Analysis of Lysergic Acid Diethylamide (LSD) and 2-oxo-3-hydroxy-LSD in Urine by Automated Extraction and Liquid Chromatography-Tandem Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkad012
Abstract: Recently, lysergic acid diethylamide (LSD) has become a resurgent drug of abuse. The detection of LSD is problematic because of the low dosage taken by users, light and heat sensitivity of the analyte, and the… read more here.
Keywords: oxo hydroxy; diethylamide lsd; acid diethylamide; lysergic acid ... See more keywords
Re-evaluation of the discriminative stimulus effects of lysergic acid diethylamide with male and female Sprague-Dawley rats
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000589
Abstract: Recent discoveries from clinical trials with psychedelic-assisted therapy have led to a resurgence of interest in the psychopharmacology of lysergic acid diethylamide (LSD). Preclinical drug discrimination is an invaluable tool to investigate the neurochemical mechanisms… read more here.
Keywords: discriminative stimulus; dawley rats; lysergic acid; male female ... See more keywords
Effects of repeated lysergic acid diethylamide (LSD) on the mouse brain endocannabinoidome and gut microbiome
Sign Up to like & getrecommendations! Published in 2022 at "British Journal of Pharmacology"
DOI: 10.1111/bph.15977
Abstract: Psychedelics elicit prosocial, antidepressant and anxiolytic effects via neuroplasticity, neurotransmission and neuro‐immunomodulatory mechanisms. Whether psychedelics affect the brain endocannabinoid system and its extended version, the endocannabinoidome (eCBome) or the gut microbiome, remains unknown. read more here.
Keywords: effects repeated; lysergic acid; brain; gut microbiome ... See more keywords
Serotonin type 5A receptor antagonists inhibit D-lysergic acid diethylamide discriminatory cue in rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881119867603
Abstract: Purpose: Like other psychedelics, D-lysergic acid diethylamide (LSD) affects numerous serotonin receptors, and according to the current dogma, the 5-HT2A receptors are considered the main target for its hallucinogenic effects. LSD, however, also displays agonistic… read more here.
Keywords: lsd; acid diethylamide; receptor antagonists; receptor ... See more keywords
Identification of 1-Butyl-Lysergic Acid Diethylamide (1B-LSD) in Seized Blotter Paper Using an Integrated Workflow of Analytical Techniques and Chemo-Informatics
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DOI: 10.3390/molecules25030712
Abstract: The rapid dispersion of new psychoactive substances (NPS) presents challenges to customs services and analytical laboratories, which are involved in their detection and characterization. When the seized material is limited in quantity or of a… read more here.
Keywords: diethylamide lsd; acid diethylamide; chemo informatics; identification ... See more keywords