LAUSR

About LAUSR
Donate
Contact Us

Follow us:

You are not signed in:

Sign Up!


   Articles with "lysin" as a keyword



Analysis of the cell wall binding domain in bacteriocin-like lysin LysL from Lactococcus lactis LAC460

Sign Up to like & get
recommendations! Published in 2024 at "Archives of Microbiology"

DOI: 10.1007/s00203-024-04066-5

Abstract: Wild-type Lactococcus lactis strain LAC460 secretes prophage-encoded bacteriocin-like lysin LysL, which kills some Lactococcus strains, but has no lytic effect on the producer. LysL carries two N-terminal enzymatic active domains (EAD), and an unknown C-terminus… read more here.

Keywords: lac460; hgfpuv cbdlysl; lysin; lactis ... See more keywords

Intrinsic resistance of Enterococcus faecalis strains to ΦEf11 phage endolysin is associated with the presence of ΦEf11 prophage

Sign Up to like & get
recommendations! Published in 2020 at "Archives of Virology"

DOI: 10.1007/s00705-020-04861-7

Abstract: The use of bacteriophage-encoded murein hydrolases (endolysins) is being actively explored as a means of controlling multidrug-resistant pathogens. Previously, we isolated and characterized one such enzyme, the phage ΦEf11 ORF28 lysin, which demonstrated profound antimicrobial… read more here.

Keywords: lysin; ef11; phage; enterococcus faecalis ... See more keywords

A Choline-Recognizing Monomeric Lysin, ClyJ-3m, Shows Elevated Activity against Streptococcus pneumoniae

Sign Up to like & get
recommendations! Published in 2020 at "Antimicrobial Agents and Chemotherapy"

DOI: 10.1128/aac.00311-20

Abstract: Streptococcus pneumoniae is a leading pathogen for bacterial pneumonia, which can be treated with bacteriophage lysins harboring a conserved choline binding module (CBM). Such lysins regularly function as choline-recognizing dimers. Previously, we reported a pneumococcus-specific… read more here.

Keywords: choline recognizing; streptococcus; activity; clyj ... See more keywords

Lysin LysMK34 of Acinetobacter baumannii Bacteriophage PMK34 Has a Turgor Pressure-Dependent Intrinsic Antibacterial Activity and Reverts Colistin Resistance

Sign Up to like & get
recommendations! Published in 2020 at "Applied and Environmental Microbiology"

DOI: 10.1128/aem.01311-20

Abstract: A. baumannii is one of the most challenging pathogens for which development of new and effective antimicrobials is urgently needed. Colistin is a last-resort antibiotic, and even colistin-resistant A. baumannii strains exist. Here, we present… read more here.

Keywords: turgor pressure; baumannii; activity; colistin ... See more keywords
Photo by ldxcreative from unsplash

Exploiting Broad-Spectrum Chimeric Lysin to Cooperate with Mupirocin against Staphylococcus aureus-Induced Skin Infections and Delay the Development of Mupirocin Resistance

Sign Up to like & get
recommendations! Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.05050-22

Abstract: Staphylococcus aureus, as an Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacter species (ESKAPE) pathogen, can escape the elimination of existing antibiotics. At present, phages and phage lysins against S. aureus… read more here.

Keywords: staphylococcus aureus; resistance; mupirocin; aureus ... See more keywords

Antimicrobial activity of bovine NK-lysin-derived peptides on Mycoplasma bovis

Sign Up to like & get
recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0197677

Abstract: Antimicrobial peptides (AMPs) are a diverse group of molecules which play an important role in the innate immune response. Bovine NK-lysins, a type of AMP, have been predominantly found in the granules of cytotoxic T-lymphocytes… read more here.

Keywords: lysin; microscopy; bovine; antimicrobial activity ... See more keywords

Genomic Variant in NK-Lysin Gene Is Associated with T Lymphocyte Subpopulations in Pigs

Sign Up to like & get
recommendations! Published in 2022 at "Genes"

DOI: 10.3390/genes13111985

Abstract: As an antimicrobial peptide, NK-lysin (NKL) plays an important role in the innate immune system of organisms. In this study, 300 piglets (68 Landrace pigs, 158 Large White pigs and 74 Songliao Black pigs) were… read more here.

Keywords: cd4 cd8; associated lymphocyte; lymphocyte subpopulations; gene ... See more keywords

Functional Characterization of Porcine NK-Lysin: A Novel Immunomodulator That Regulates Intestinal Inflammatory Response

Sign Up to like & get
recommendations! Published in 2021 at "Molecules"

DOI: 10.3390/molecules26144242

Abstract: Porcine NK-Lysine (PNKL) is a new antimicrobial peptide (AMP) identified in the small intestine. In this study, PNKL protein was obtained through heterologous expression in Escherichia coli and was estimated by SDS-PAGE at 33 kDa.… read more here.

Keywords: lysin; coli k88; functional characterization; ipec cells ... See more keywords

Porcine Recombinant NK-Lysin Inhibits the Growth and Metastasis of Murine Hepatocellular Carcinoma In Vivo

Sign Up to like & get
recommendations! Published in 2025 at "Molecules"

DOI: 10.3390/molecules30061234

Abstract: Porcine recombinant NK-lysin (prNK-lysin) has been shown to inhibit the proliferation and metastasis of hepatocellular carcinoma (HCC) cells in vitro. However, its effects on the proliferation and metastasis of HCC cells in vivo remain unclear.… read more here.

Keywords: prnk lysin; lysin; porcine recombinant; metastasis ... See more keywords