Oral Delivery of Protein Drugs via Lysine Polymer-Based Nanoparticle Platforms.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202300311
Abstract: Oral delivery of proteins has opened a new perspective for the treatment of different diseases. However, advances of oral protein formulation are usually hindered by protein susceptibility and suboptimal absorption in the gastrointestinal tract (GIT).… read more here.
Keywords: lys aapeas; delivery protein; oral delivery; lysine ... See more keywords
Glycyl‐l‐histidyl‐l‐lysine‐Cu2+ rescues cigarette smoking‐induced skeletal muscle dysfunction via a sirtuin 1‐dependent pathway
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13213
Abstract: Skeletal muscle dysfunction is an important co‐morbidity in patients with chronic obstructive pulmonary disease (COPD) and is significantly associated with increased mortality. Oxidative stress has been demonstrated an important trigger for COPD‐related skeletal muscle dysfunction.… read more here.
Keywords: skeletal muscle; muscle; glycyl histidyl; lysine ... See more keywords
Impact of enteral arginine supplementation on lysine metabolism in humans: A proof‐of‐concept for lysine‐related inborn errors of metabolism
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Inherited Metabolic Disease"
DOI: 10.1002/jimd.12233
Abstract: Patients with lysine‐related inborn errors of metabolism (pyridoxine‐dependent epilepsy [PDE] and glutaric aciduria type 1 [GA1]), follow a lysine‐restricted diet with arginine‐fortified lysine‐free amino acid formula and additional oral arginine supplementation as a newer therapy… read more here.
Keywords: lysine related; lysine; errors metabolism; arginine ... See more keywords
Site‐Specific Systematic Analysis of Lysine Modification Crosstalk
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700292
Abstract: Research has revealed that post‐translational modifications (PTMs) that occur at lysine (PLMs) can cooperatively regulate various biological processes by crosstalk. However, the trend of the crosstalk between multiple PLMs and the properties of PLM crosstalk… read more here.
Keywords: site specific; analysis; lysine; specific systematic ... See more keywords
Dimethyl-Labeling-Based Quantification of the Lysine Acetylome and Proteome of Plants.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7225-8_5
Abstract: Photorespiratory enzymes in different cellular compartments have been reported to be posttranslational modified by phosphorylation, disulfide formation, S-nitrosylation, glutathionylation, and lysine acetylation. However, not much is known yet about the function of these modifications to… read more here.
Keywords: dimethyl labeling; lysine; quantification lysine; lysine acetylation ... See more keywords
Determination of lysine content based on an in situ pretreatment and headspace gas chromatographic measurement technique
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-0998-6
Abstract: AbstractThis work reports on a simple method for the determination of lysine content by an in situ sample pretreatment and headspace gas chromatographic measurement (HS-GC) technique, based on carbon dioxide (CO2) formation from the pretreatment… read more here.
Keywords: lysine; measurement; lysine content; determination lysine ... See more keywords
Effects of Amino Acids and Overexpression of dapA Gene on the Production of ε-Poly-L-lysine by Streptomyces diastatochromogenes Strains.
Sign Up to like & getrecommendations! Published in 2021 at "Current microbiology"
DOI: 10.1007/s00284-021-02510-z
Abstract: In this study, the strain Streptomyces diastatochromogenes 6#-7, which efficiently synthesizes ε-Poly-L-lysine, was studied and the effects of 18 amino acids and overexpression of dapA gene on the fermentation efficiency of ε-PL by S. diastatochromogenes… read more here.
Keywords: overexpression; production; lysine; fermentation ... See more keywords
Comprehensive assessment of the l-lysine production process from fermentation of sugarcane molasses
Sign Up to like & getrecommendations! Published in 2017 at "Bioprocess and Biosystems Engineering"
DOI: 10.1007/s00449-017-1766-2
Abstract: Abstractl-Lysine is an essential amino acid that can be produced by chemical processes from fossil raw materials, as well as by microbial fermentation, the latter being a more efficient and environmentally friendly procedure. In this… read more here.
Keywords: production process; lysine; fermentation; process ... See more keywords
Post-translational formation of hypusine in eIF5A: implications in human neurodevelopment.
Sign Up to like & getrecommendations! Published in 2021 at "Amino acids"
DOI: 10.1007/s00726-021-03023-6
Abstract: Hypusine [Nε-(4-amino-2-hydroxybutyl)lysine] is a derivative of lysine that is formed post-translationally in the eukaryotic initiation factor 5A (eIF5A). Its occurrence at a single site in one cellular protein defines hypusine synthesis as one of the… read more here.
Keywords: eif5a; hypusine; lysine; post translational ... See more keywords
The conversion of l-lysine into l-β-lysine: the role of 5′-deoxyadenosyl radical and water—a DFT study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-020-04639-3
Abstract: In the current study, we deal with the crucial role of 5′-deoxyadenosyl radical and water in the mechanism of the conversion of l -lysine into l -β-lysine. The DFT (density functional theory)–B3LYP method coupled with… read more here.
Keywords: water; lysine; radical water; deoxyadenosyl radical ... See more keywords
Effect of sinusoidal Taylor vortex flow on cooling crystallization of L-lysine
Sign Up to like & getrecommendations! Published in 2017 at "Korean Journal of Chemical Engineering"
DOI: 10.1007/s11814-017-0059-4
Abstract: An elliptical Couette-Taylor (ECT) crystallizer with a unique sinusoidal Taylor vortex flow was developed to promote the recovery and size distribution of L-lysine crystals in cooling crystallization. When using the ECT crystallizer, the recovery was… read more here.
Keywords: taylor vortex; lysine; crystallization; crystallizer ... See more keywords